Stability Indicating Method Development and Validation for the Simultaneous Estimation of Azilsartan and Chlorthalidone in their Bulk and Pharmaceutical Dosage Forms by RP-UPLC
Upender Rao Eslawath,
Kannappan Kannappan N,
Venkateshwarlu Venkateshwarlu L
et al.
Abstract:Aim: The present study is aimed towards developing and validating novel RP-UPLC analytical method for the analysis of Azilsartan and Chlorthalidone in their pharmaceutical formulations and to carry out stability studies by forced degradation to ascertain the stability of selected drugs. The proposed method was challenging as the method used in the study is novel for the estimation of antihypertensive drugs. Materials and Methods: The solubility studies of Azilsartan and Chlorthalidone were carried out at 25°C … Show more
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