Stability Indicating Hplc Method using Core Shell Stationary Phase for the Determination of Related Substances in Levocetirizine Dihydrochloride Oral Solution
Abstract:Introduction: Levocetirizine (LCZ) is a new generation antihistamine drug used for the allergic symptoms resulting from various diseases. The present research work focuses on the development of a simple and precise HPLC method for the effective separation and quantitative determination of LCZ and its impurities. Objectives: Eight potential related impurities of LCZ were separated and identified in the bulk drug as well as oral solution dosage form. Results: The separation was achieved on a core shell stationar… Show more
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