Stability, Hopf Bifurcation and Numerical Simulation of an HIV Model with Two Modes of Transmission and with Cellular and Humoral Immunity
Zeynab Hemmatzadeh,
Vahid Roomi,
Tohid Kasbi Gharahasanlou
Abstract:In this paper, we incorporate immune systems containing Cytotoxic T lymphocyte and humoral immunity into a general human immunodeficiency viruses infection model, which also considers logistic growth for target cells and both modes of spread, cell-to-cell and cell-free represents, by linear functions. We derive five threshold parameters which are used to study the existence of equilibria. By considering the characteristic equations, the local stability of disease-free and immune-free equilibria is investigated… Show more
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