“…In addition, the framework presented here could serve as a basis for extensions to (i) higher order time-discretization methods via, for example, symmetrization [17] or time-extrapolation [21,22]; (ii) different PDE systems in each Ω l region deriving, for example, from Navier-Stokes equations [18], fluid-structure interactions [19,32], non-Newtonian fluid flows [33] or porous media flows [34,35]; and (iii) different spatial discretization methods for each PDE problem including, for example, higher order finite element methods [36] or hybridizable discontinuous Galerkin methods [34,37,38]. The extensions mentioned above are relatively straight-forward, since the algorithms described in the corresponding references are directly implementable on that presented in this work.…”