This study aims to determine the epidemic preparedness of junior high school students who have studied the respiratory system against the Covid-19 outbreak. Classification of diseases including pandemics, endemics or epidemics based on the area affected in a certain time. The increasing epidemic of Covid-19 has an impact on health, social and economy, especially in developing countries so that epidemic preparedness needs to be carried out for timely detection of epidemics followed by prompt and appropriate responses. This type of research is a qualitative descriptive study, with the research design used is survey research. The subject of this study consisted of 554 junior high school students in several areas including West Java, Central Java, Special Region of Yogyakarta, East Java, and Batam. The students have learned the respiratory system. Data collection was carried out in May 2020. The data collection method used was an online questionnaire through Google Form about epidemic preparedness especially Covid-19 which is a respiratory system disease. The results of the analysis showed that endemic preparedness in 8th and 9th grade junior high school students in several schools in Indonesia, showed an index of 73.97. That number is between 65 to 79 so that it can be categorized as advanced in endemic preparedness in the face of the current Covid-19 pandemic outbreak. The conclusion of this study is that the epidemic preparedness of junior high school students on the Covid-19 outbreak falls into the “Advanced” category.