St-Segment Elevation Myocardial Infarction in Young Patients: Risk Factors and Prognosis

Abstract

Objective:ST elevation myocardial infarction (STEMI) is a common event in old adult. However, STEMI remains poorly described in young. We aimed to assess risk factors, angiographic results and in-hospital prognosis in young < 45 years presented with STEMI.Design and method:All patients hospitalized for STEMI and aged between 18 and 65 years were retrospectively enrolled in this study. Young patients < 45 years were compared to those (less young) aged more than 45 and less than 65 years. Demographic informations, risk factors, angiographic profile and prognosis were collected.Results:Among 1210 STEMI patients, 251 (20.7%) patients were young. Two young patients and four less young did not have coronary angiography because of premature death.No significant difference was demonstrated in term of in-hospital complications such as acute heart failure, cardiogenic shock, ventricular arrhythmia, atrio-ventricular block between the two groups. Compared to less young patients, in-hospital mortality accounted for 3.40% in young versus 4.6% (p = 0.3). Smoking was identified as a significant predictors factors of mortality (p = 0.015) in young patients.Conclusions:In contrast to “less young” patients, STEMI in young is characterized by predominance of smoking, cannabis consumption and family history of CAD as risk factors, more MINOCA and diffuse coronary lesions with no difference in term of in-hospital mortality.