SSRI Sexual Dysfunction: A Female Perspective

Hensley, Paula L.; Nurnberg, H. George

doi:10.1080/00926230252851267

Cited by 29 publications

(24 citation statements)

References 15 publications

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“…29,30 The selective serotonin reuptake inhibitors appear to be associated with especially high rates of sexual dysfunction and whereas men taking selective serotonin reuptake inhibitors report higher rates of sexual side effects than women, the dysfunction experienced by women seems to be more severe. 29,31 Finally, just as cardiovascular problems are good markers for sexual problems (and vice versa), our data suggest that depression can be investigated in a similar way, that is, physicians who note that their patients are depressed may want to inquire about their sexual function and patients who are having problems with sex should be queried about their mood state.…”

Section: Discussionmentioning

confidence: 75%

A population-based survey of sexual activity, sexual problems and associated help-seeking behavior patterns in mature adults in the United States of America

et al. 2009

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To study sexual activity, the prevalence of sexual dysfunction and related help-seeking behaviors among mature adults in the United States of America, a telephone survey was conducted in [2001][2002]. A total of 1491 individuals (742 men/749 women) aged 40-80 years completed the survey. Overall, 79.4% of men and 69.3% of women had engaged in sexual intercourse during the 12 months preceding the interview. Early ejaculation (26.2%) and erectile difficulties (22.5%) were the most common male sexual problems. A lack of sexual interest (33.2%) and lubrication difficulties (21.5%) were the most common female sexual problems. Less than 25% of men and women with a sexual problem had sought help for their sexual problem(s) from a health professional. Many men and women in the United States report continued sexual interest and activity into middle age and beyond. Although a number of sexual problems are highly prevalent, few people seek medical help.

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Section: Discussionmentioning

confidence: 75%

A population-based survey of sexual activity, sexual problems and associated help-seeking behavior patterns in mature adults in the United States of America

et al. 2009

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“…Women may have more severe SSRI sexual side effects, including orgasm delay, than men. 41 In preliminary work, we controlled specifically for depressive symptoms and found a similar relationship with SSRI use.…”

Section: Discussionmentioning

confidence: 99%

Correlates of Sexual Satisfaction Among Sexually Active Postmenopausal Women in the Women’s Health Initiative-Observational Study

et al. 2008

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BACKGROUND: Satisfaction with sexual activity is important for health-related quality of life, but little is known about the sexual health of postmenopausal women.OBJECTIVE: Describe factors associated with sexual satisfaction among sexually active postmenopausal women. DESIGN:Cross-sectional analysis.PARTICIPANTS: All members of the Women's Health Initiative-Observational Study (WHI-OS), ages 50-79, excluding women who did not respond to the sexual satisfaction question or reported no partnered sexual activity in the past year (N=46,525). MEASUREMENTS:Primary outcome: dichotomous response to the question, "How satisfied are you with your sexual activity (satisfied versus unsatisfied)?" Covariates included sociodemographic factors, measures of physical and mental health, and gynecological variables, medications, and health behaviors related to female sexual health. RESULTS:Of the cohort, 52% reported sexual activity with a partner in the past year, and 96% of these answered the sexual satisfaction question. Nonmodifiable factors associated with sexual dissatisfaction included age, identification with certain racial or ethnic groups, marital status, parity, and smoking history. Potentially modifiable factors included lower mental health status and use of SSRIs. The final model yielded a c-statistic of 0.613, reflecting only a modest ability to discriminate between the sexually satisfied and dissatisfied.CONCLUSIONS: Among postmenopausal women, the variables selected for examination yielded modest ability to discriminate between sexually satisfied and dissatisfied participants. Further study is necessary to better describe the cofactors associated with sexual satisfaction in postmenopausal women.

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“…[34][35][36] Selective serotonin reuptake inhibitors (SSRIs) have been reported to be associated with particularly high rates of sexual dysfunction and, while men report higher rates of sexual side effects from SSRIs than do women, women seem to experience more severe dysfunction with these agents. 35,37 A significant association between depression and erectile dysfunction among men in Brazil has been reported previously. [12][13][14] However, the data from GSSAB indicate that depression is also associated with other male sexual problems, namely early ejaculation and a lack of sexual interest.…”

Section: Help-seeking Behaviormentioning

confidence: 99%

Prevalence of sexual problems and related help-seeking behaviors among mature adults in Brazil: data from the global study of sexual attitudes and behaviors

et al. 2005

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CONTEXT AND OBJECTIVE: Relatively little is known about the usual frequency of sexual activity and how older individuals cope with sexual problems. The objective was to study sexual activity, prevalence of sexual problems and related help-seeking behaviors among middle-aged and older men and women in Brazil. DESIGN AND SETTING: Population survey, by Fundação Oswaldo Cruz. METHODS: Interviews were held with 1,199 Brazilians aged 40-80 years (471 men and 728 women). The standardized questionnaire investigated demographics, general health, sexual behavior, attitudes and beliefs. RESULTS: Overall, 92.6% of men and 58.3% of women had had sexual intercourse during the preceding year. More than half of the men and women had done so more than once a week. Early ejaculation (30.3%) was the commonest male sexual problem, followed by inability to reach orgasm (14.0%), erectile difficulties (13.1%) and lack of sexual interest (11.2%). For women, the commonest sexual problems were lubrication difficulties (23.4%) and lack of sexual interest (22.7%). Depression was a significant correlate of sexual problems, for men and women. More women than men had sought help for sexual problem(s) from a healthcare professional. CONCLUSIONS: The findings highlight the importance of encouraging greater use of available healthcare services, including consultation with a medical doctor regarding sexual health. This should not only enable men and women to maintain satisfactory sexual function well into their later years, but may also result in overall improvement in the quality of healthcare.

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SSRI Sexual Dysfunction: A Female Perspective

Cited by 29 publications

References 15 publications

A population-based survey of sexual activity, sexual problems and associated help-seeking behavior patterns in mature adults in the United States of America

A population-based survey of sexual activity, sexual problems and associated help-seeking behavior patterns in mature adults in the United States of America

Correlates of Sexual Satisfaction Among Sexually Active Postmenopausal Women in the Women’s Health Initiative-Observational Study

Prevalence of sexual problems and related help-seeking behaviors among mature adults in Brazil: data from the global study of sexual attitudes and behaviors

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