1998
DOI: 10.1016/s0171-9335(98)80053-8
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ß1B Integrin interferes with matrix assembly but not with confluent monolayer polarity, and alters some morphogenetic properties of FRT epithelial cells

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Cited by 12 publications
(16 citation statements)
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“…The ␤1B isoform is expressed primarily in skin and liver, where it constitutes a minority of the ␤1 protein (Balzac et al, 1993). To date, no function of ␤1B has been demonstrated in situ, but there have been a number of studies of the properties of the isoform in cultured cells (Balzac et al, 1993(Balzac et al, , 1994Cali et al, 1998;Retta et al, 1998;Armulik et al, 2000). Overall, this work indicates that ␤1B is deficient in both "outside in" and "inside out" integrin signaling.…”
Section: Similarity To Mammalian ␤ Subunit Variantsmentioning
confidence: 76%
“…The ␤1B isoform is expressed primarily in skin and liver, where it constitutes a minority of the ␤1 protein (Balzac et al, 1993). To date, no function of ␤1B has been demonstrated in situ, but there have been a number of studies of the properties of the isoform in cultured cells (Balzac et al, 1993(Balzac et al, , 1994Cali et al, 1998;Retta et al, 1998;Armulik et al, 2000). Overall, this work indicates that ␤1B is deficient in both "outside in" and "inside out" integrin signaling.…”
Section: Similarity To Mammalian ␤ Subunit Variantsmentioning
confidence: 76%
“…In particular, we have shown that the unique cytoplasmic sequences of ␤ 1 B and ␤ 1 D endow these molecules with distinctive functional properties with respect to a number of cellular functions (Balzac et al, 1994;Belkin et al, 1997;Belkin and Retta, 1998;Calì et al, 1998;Retta et al, 1998). In particular, we have shown that the unique cytoplasmic sequences of ␤ 1 B and ␤ 1 D endow these molecules with distinctive functional properties with respect to a number of cellular functions (Balzac et al, 1994;Belkin et al, 1997;Belkin and Retta, 1998;Calì et al, 1998;Retta et al, 1998).…”
Section: ␤ 1 Effect Over ␣ V Integrins Occurs Irrespective Of the Typmentioning
confidence: 88%
“…We used the mouse NIH/3T3 (ATCC CRL-1658), GD25 , sEnd.1 (Williams et al, 1988) and N1E-115 (ATCC CRL-2263), the human HEK293 (ATCC CRL-1573), MCF10A (ATCC CRL-10317), T-47D (ATCC HTB-133) and ECV-304 (ATCC CRL-1998), the monkey COS7 (ATCC CRL-1651), and the rat FRT (Cali et al, 1998) cell lines. All cell lines were cultured in Dulbecco's modified Eagle's medium (DMEM), containing 10% foetal calf serum (FCS), 2 mM glutamine and penicillin/streptomycin (50 IU/ ml, 50 mg/ml), except FRT, T-47D and MCF10A cells cultured in Coon's F12, RPMI 1640 and MEGM medium, respectively.…”
Section: Cell Lines and Tissuesmentioning
confidence: 99%