Squash–prep cytology in the diagnosis of canine and feline nervous system lesions: a study of 42 cases

Abstract

Although the current series of cases is relatively small, cytologic evaluation of squash preparations can be considered a fairly accurate and reliable tool in the diagnosis of NS lesions.

The Central Nervous System

“…The authors conclude that intraoperative diagnosis with stereotactic biopsy has high validity and that immediate treatment based on smear preparations can be justifi ed. Although in a much smaller series of cases, similar results have been published in veterinary literature as well, with a satisfactory cytologic diagnosis obtained in more than 90% of examined cases (De Lorenzi et al, 2006).…”

“…14-56A). Two choroid plexus carcinomas were cytologically misdiagnosed as choroid plexus papillomas (De Lorenzi et al, 2006). Both of these tumors occurred within a ventricular site and consisted of large, pedunculated, friable masses that presented cytologically as well-formed papillary structures, usually showing a fi ne fi brovascular core covered by uniform, cuboidal or columnar epithelium having minimal cytologic atypia with moderate pleomorphism (Fig.…”

“…All of these techniques are currently used in cytologic evaluations of human patients (Bigner, 1997) and to a limited extent in veterinary medicine (De Lorenzi et al, 2006;Moissoinier et al, 2002;Vernau et al, 2001). There may be increased demand and/or need for development of special preparative techniques such as cell blocks and immunocytochemistry for more precise identifi cation of primary or metastatic tumors, infl ammatory cell types, or immunophenotype of malignant or nonmalignant lymphoid proliferations.…”

“…Myelography, MRI, and CT are imaging tools used currently to identify tumors of the brain and spinal cord. Fine-needle aspirations, crush preparations (De Lorenzi et al, 2006;Moissonier et al, 2002), and incisional cutting needles have been used to obtain cytologic and tissue samples for biopsy. The cytologic features of meningiomas have been discussed in several reports (Zimmerman et al, 2000;Hopkins et al, 1995).…”

Press Imprint Smear: A Rapid, Simple, and Cheap Method for the Diagnosis of Cutaneous Leishmaniasis Caused by Leishmania (Viannia) braziliensis

“…On a firm surface, the tissue fragment between both glass slides was squeezed (squashed). 6,7 Pressure on the middle of the slides was made, and therefore, the juice and tissue cells were spread on both slides' surfaces that were in contact with the sample (Figure 2A and B). To avoid smears being too thick, slight movements were made (Supplemental Videos 1 and 2).…”