Square-wave adsorptive stripping voltammetry of menadione (vitamin K3)

Viré, Jean‐Claude; Maali, Nagwa Abo El; Patriarche, Gaston; Christian, Gary D.

doi:10.1016/0039-9140(88)80235-2

Cited by 39 publications

(18 citation statements)

References 2 publications

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“…The signal intensity of SWSV was found to be 10 times higher that that of DPSV. Similar observation was found with SWSV for the trace analysis of few other drugs [29][30][31][32]. …”

Section: Constant Potential Chronoamperometrysupporting

confidence: 86%

Electrochemical detection of celecoxib at a polyaniline grafted multiwall carbon nanotubes modified electrode

Manesh

Santhosh

Komathi

et al. 2008

Analytica Chimica Acta

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“…The signal intensity of SWSV was found to be 10 times higher that that of DPSV. Similar observation was found with SWSV for the trace analysis of few other drugs [29][30][31][32]. …”

Section: Constant Potential Chronoamperometrysupporting

confidence: 86%

Electrochemical detection of celecoxib at a polyaniline grafted multiwall carbon nanotubes modified electrode

Manesh

Santhosh

Komathi

et al. 2008

Analytica Chimica Acta

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“…advantages along with sensitivity and rapidity of the SWV were documented in connection with the trace analysis of several other drugs. [18][19][20] Square-wave voltammetry was therefore used for further measurements.…”

Section: Resultsmentioning

confidence: 99%

Enhanced Electrochemical Detection of Ketorolac Tromethamine at Polypyrrole Modified Glassy Carbon Electrode

et al. 2007

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Ketorolac tromethamine, KT ((k)-5-benzoyl-2,3-dihydro-1H pyrrolizine-l-carboxylic acid), is a member of the pyrrolopyrrole group of non-steroidal anti-inflammatory drugs 1 with cyclooxygenase inhibitory activity. 2 KT is a non-opioid analgesic which exists in three crystalline forms that are soluble in water. KT, when administered systemically, has demonstrated analgesic, anti-inflammatory, and anti-pyretic activity.3 KT is used for acute and short-term relief of pain. It increases the plasma levels of salicylates due to a decrease in plasma protein binding. The most frequent adverse events reported with the use of KT are transient stinging and burning on instillation. These events were reported for up to 40% of patients who were administered the drug in clinical trials. Other adverse events occurring approximately 1 to 10% of the time during treatment with KT included allergic reactions, corneal edema, iritis, ocular inflammation, ocular irritation, superficial keratitis and superficial ocular infections. Hence, a highly selective and accurate analytical method for measuring KT is desired, probably for optimizing its therapy and minimizing its side effects.For electrochemical detection and estimation, conducting polymers have recently been used as modifying substrates, because they can act as an electronic transducer for charged species binding to their surface. Biochemical units can also be covalently grafted to the polymer backbone, and subsequently used for detection. Polypyrrole (Ppy), modified onto platinum substrates was used to reduce the interference signal caused by ascorbic and uric acids on an ammonia amperometric sensor in aqueous solutions. 4 A platinum electrode modified by an electrogenerated overoxidized Ppy was used as a substrate for biosensor application. 5Miniaturized and disposable amperometric biosensors were developed for glucose determination in serum. A simple and label-free electrochemical sensor for the recognition of DNA hybridization was reported based on a functionalized conducting copolymer, poly [pyrrole-co-4-(3-pyrrolyl)butanoic acid]. 6 Several analytical techniques were developed for the determination of KT from the bulk drug, which included nonaqueous titration, thin-layer chromatography, UV spectrophotometry, 7,8 and high-performance liquid chromatography methods, 9 electrochromatography, 10 reversed-phase liquid chromatography-mass spectrometry 11 and flow-injection analysis.12 KT has been determined by gas chromatography-mass spectrometry using diazopropane. 13Studies in human serum have been performed. [14][15][16][17] However, these methods require tedious sample preparation and time-consuming experimental procedures. A simple and sensitive method is therefore needed for the fast, accurate detection and estimation of KT.In this work, an electro-analytical approach was developed for the detection and determination of KT by square-wave stripping voltammetry using a Ppy modified glassy carbon (GC/Ppy) electrode in an acetate buffer (pH 5.5). The method was also tested for t...

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“…Wang et al (8) 1678 SONG, HE, AND GUO ORDER REPRINTS used cathodic stripping voltammetry in sodium sulfate supporting electrolyte (pH 1.70-1.85) at reductive peak of À0.064 V (vs. SCE), with the detection limit of 1.0 Â 10 À9 mol/L. Vire et al (9) described a square-wave adsorptive anodic stripping voltammetry method in 0.3 mol/L perchloric acid medium. The deposition time was 10 min.…”

Section: Introductionmentioning

confidence: 98%

Determination of Menadione Based on Its Polarographic Catalytic Wave in the Presence of Potassium Iodinate

Song

Guo

2001

Analytical Letters

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A method for the determination of menadione was proposed. In 0.2 mol/L HOAc-NaOAc (pH 4.7) buffer solution containing 4.0 Â 10 À3 mol/L KIO 3 , menadione yields a well-defined polarographic catalytic wave with a peak potential of À0.95 V (vs. SCE). The second order derivative peak current is linearly proportional to the menadione concentration in the range of 4.0 Â 10 À8 -2.0 Â 10 À6 mol/L with the correlation coefficient of 0.999 (n ¼ 8). The detection limit is 2.0 Â 10 À8 mol/L. The sensitivity of the catalytic wave is 10 times higher than that of the corresponding reduction wave in the absence of KIO 3 . The proposed method was used to directly determine the 1677 ORDER REPRINTS menadione contents in clinical injections in good agreement with the labeled amount without preseparation. The mechanism of polarographic catalytic wave of menadione was discussed. The polarographic reduction wave of menadione itself in the acetate buffer solution is ascribed to that the carbonyl group of menadione is reduced in consecutive two electrons and two protons addition to hydroquinone via semiquinone (quinone-hydroquinone) free radical intermediates.In the presence of KIO 3 , the carbonyl group of menadione is chemically regenerated due to oxidation of semiquinone free radical intermediates by KIO 3 and a series of its derived species formed during six-electron successive reduction process. The maximum current of the first charge transfer is enhanced, and the second electroreduction step of menadione is inhibited.

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Square-wave adsorptive stripping voltammetry of menadione (vitamin K3)

Cited by 39 publications

References 2 publications

Electrochemical detection of celecoxib at a polyaniline grafted multiwall carbon nanotubes modified electrode

Electrochemical detection of celecoxib at a polyaniline grafted multiwall carbon nanotubes modified electrode

Enhanced Electrochemical Detection of Ketorolac Tromethamine at Polypyrrole Modified Glassy Carbon Electrode

Determination of Menadione Based on Its Polarographic Catalytic Wave in the Presence of Potassium Iodinate

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