Square structured photonic crystal fiber based THz sensor design for human body protein detection

Islam, Md. Aminul; Islam, Mohammad Rakibul; Naser, Ahmed Mujtaba Al; Anzum, Fariha; Jaba, Fatema Zerin

doi:10.1007/s10825-020-01606-2

Cited by 37 publications

(13 citation statements)

References 55 publications

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“…The relative sensitivity coefficient is calculated by [57]:

r=\frac{{n}_{r}}{\mathrm{Re}[{n}_{\text{eff}}]}P

here n r refers to the analyte's RI, Re( n eff ) refers to the real component of effective mode index, and p refers to the fractional power going through the core. It is denoted by the equation below [58]:

P=\frac{{\int }_{\text{sample}}\mathrm{Re}[{E}_{x}{H}_{y}-{E}_{y}{H}_{x}]dxdy}{{\int }_{\text{total}}\mathrm{Re}[{E}_{x}{H}_{y}-{E}_{y}{H}_{x}]dxdy}\times 100\%

here E x and H x denote the transverse electric and magnetic fields, and Ey and Hy represent the longitudinal electric and magnetic fields.…”

Section: Performance Analysismentioning

confidence: 99%

Design of a hexagonal outlined porous cladding with vacant core photonic crystal fibre biosensor for cyanide detection at THz regime

Islam

Naser

Jaba

et al. 2022

IET Optoelectronics

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A hexagonal outlined porous cladding with vacant core photonic crystal fibre (HOPC‐VC‐PCF) sensor using Zeonex has been presented, which can detect cyanides at the THz regime. Cyanides are incredibly lethal chemicals to humans as they can rapidly cause impairment or even death; such harmful substances must be identified precisely. The proposed model has been analysed at a broad spectrum of THz regimes for three different analytes, and the numerical investigation is performed using the Finite element method (FEM). Simulation results exhibit that at optimum design parameters, extremely high sensitivity of 99.75%, negligible confinement loss of 0.5 × 10−13 cm−1, extremely low and flat dispersion of 0.12 ps THz/cm, and other excellent features were obtained. The performance analysis and the design methodology have been depicted in detail. Due to the simplistic design, fabrication of the model is easily achievable by current technology. The remarkable sensing capabilities will not only make it suited in chemicals analysis but also will play vital roles in other applications as well.

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“…The relative sensitivity coefficient is calculated by [57]:

r=\frac{{n}_{r}}{\mathrm{Re}[{n}_{\text{eff}}]}P

P=\frac{{\int }_{\text{sample}}\mathrm{Re}[{E}_{x}{H}_{y}-{E}_{y}{H}_{x}]dxdy}{{\int }_{\text{total}}\mathrm{Re}[{E}_{x}{H}_{y}-{E}_{y}{H}_{x}]dxdy}\times 100\%

here E x and H x denote the transverse electric and magnetic fields, and Ey and Hy represent the longitudinal electric and magnetic fields.…”

Section: Performance Analysismentioning

confidence: 99%

Design of a hexagonal outlined porous cladding with vacant core photonic crystal fibre biosensor for cyanide detection at THz regime

Islam

Naser

Jaba

et al. 2022

IET Optoelectronics

Self Cite

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“…The principle of additive manufacturing in 3D printing has been explored to fabricate complex sensor devices with high resolution and personalized design. The sensors may be tailored to the researchers’ and clinicians’ needs, as in the detection of nucleic acids [ 19 , 20 ], drugs [ 21 ], proteins [ 22 , 23 ], trace elements [ 24 ], and neurotransmitters [ 25 ]. In comparison to traditional subtractive manufacturing, 3D printing permits to reduce the time of sensor development.…”

Section: Introductionmentioning

confidence: 99%

Three-Dimensional Printing and Its Potential to Develop Sensors for Cancer with Improved Performance

et al. 2022

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Cancer is the second leading cause of death globally and early diagnosis is the best strategy to reduce mortality risk. Biosensors to detect cancer biomarkers are based on various principles of detection, including electrochemical, optical, electrical, and mechanical measurements. Despite the advances in the identification of biomarkers and the conventional 2D manufacturing processes, detection methods for cancers still require improvements in terms of selectivity and sensitivity, especially for point-of-care diagnosis. Three-dimensional printing may offer the features to produce complex geometries in the design of high-precision, low-cost sensors. Three-dimensional printing, also known as additive manufacturing, allows for the production of sensitive, user-friendly, and semi-automated sensors, whose composition, geometry, and functionality can be controlled. This paper reviews the recent use of 3D printing in biosensors for cancer diagnosis, highlighting the main advantages and advances achieved with this technology. Additionally, the challenges in 3D printing technology for the mass production of high-performance biosensors for cancer diagnosis are addressed.

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“…However, a high-level alignment is required and the free-space measurement has high path loss. Islam et al presented a porous core PhC fiber for chemical sensing [8] and a squared hollow-core PhC fiber sensor for protein detection [9]. The PhC fiber has the advantages of high confinement and low propagation attenuation along the fiber.…”

Section: Introductionmentioning

confidence: 99%

Sensitive and Robust Millimeter-Wave/Terahertz Photonic Crystal Chip for Biosensing Applications

et al. 2022

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In recent years terahertz (THz) technology has attracted great interest in biosensing applications. Due to the interaction between analyte and electromagnetic (EM) field, a THz resonator is sensitive to changes in the refractive index of the analyte and can be used as a thin-film sensor for rapid pathogen diagnosis. To achieve high sensitivity and reliability, the sensor should have a high Q factor, a high field concentration at the site of the analyte, and the ability to compensate for temperature effects. However, conventional metamaterial methods have a low Q factor, which may lead to ambiguous detection and no attention has been paid to address the temperature effects. Here, we present a photonic crystal (PhC) based chip consisting of a reference channel and a sensing channel with two identical PhC slot resonators. The resonance difference between the resonators is temperature invariant and can be used for analyte detection. The dual-channel PhC chip has a Q factor of 5063 and a figure of merit of 3.1 /RIU/µm (RIU is refractive index unit), which are higher than that of metamaterial sensors. The chip is designed and simulated for the W band by 3D field simulations and is verified by measurements. Our results suggest that THz PhC resonators can provide high sensitivity and high resistance to environmental effects. We anticipate our work to be a starting point for future biosensing applications.INDEX TERMS High Q factor, photonic crystal resonator, temperature invariant, terahertz, thin-film sensing.

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Square structured photonic crystal fiber based THz sensor design for human body protein detection

Cited by 37 publications

References 55 publications

Design of a hexagonal outlined porous cladding with vacant core photonic crystal fibre biosensor for cyanide detection at THz regime

Design of a hexagonal outlined porous cladding with vacant core photonic crystal fibre biosensor for cyanide detection at THz regime

Three-Dimensional Printing and Its Potential to Develop Sensors for Cancer with Improved Performance

Sensitive and Robust Millimeter-Wave/Terahertz Photonic Crystal Chip for Biosensing Applications

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