Squamous metaplasia of the peritoneum

Crome, L.

doi:10.1002/path.1700620109

Cited by 47 publications

(17 citation statements)

References 9 publications

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“…Similar findings in our opinion, have been reported by Crome 1 and by Michal 2 both in women and men. More recently, one case of squamous metaplasia is mentioned in the series of unusual appendiceal findings by Charfi et al 6 Interestingly, solid nests, as seen in 2 of the cases we report, have been mentioned in 3 out of the 7 published cases-to our knowledge.…”

Section: Discussionsupporting

confidence: 93%

“…However, associated acute appendicits as in the present cases is reported in 1 of the patients only. 1 In the 2nd case we report appendiceal mucosal inflammation was mild possibly related to the known Crohn disease the patient had, although without associated classical architectural changes or granuloma. The diffuse serosal/subserosal and muscular inflammation seen in the same appendix were rather thought to be related to the salpingeal lesions and not a persistent digestive inflammation after the medical treatments the patient had.…”

Section: Discussionmentioning

confidence: 76%

“…[1][2][3] More recently, in the 4 large reported series of appendectomies, one case of squamous metaplasia is mentioned. [4][5][6][7] Few data are available on the clinical contexts.…”

mentioning

confidence: 99%

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Acute Appendicitis and Periappendicitis Revealing Squamous and Transitional Cystic and Solid Nests in Adult Patients: Metaplasia or Vestigeal Remnants?

Handra-Luca

2016

International Surgery

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Squamous metaplasia of the appendix serosa is rare. We aimed to report the clinical and morphological features of 3 such cases. The patients presented with abdominal pain (n ¼ 1 man, 2 women; age range, 29-35 years). The clinical diagnosis was appendicitis/ periappendicitis (in the context of hydro/pyosalpinx). The surgical resected appendix showed several cystic and solid epithelial nests (1 mm and less) in the serosa/subserosa. Epithelial cells expressed p63, cytokeratin 5/6, as well as cytokeratins 7, 20, and CD10. Cystic and solid squamous and transitional epithelial nests of the appendix subserosa/ serosa in adult patients may be revealed by acute appendicitis/ periappendicitis. The presence of such lesions, metaplastic or vestigial in nature, should be acknowledged since they can be misdiagnosed with metastatic epithelial tumor nests or they may undergo malignant change.

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Section: Discussionsupporting

confidence: 93%

Section: Discussionmentioning

confidence: 76%

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Acute Appendicitis and Periappendicitis Revealing Squamous and Transitional Cystic and Solid Nests in Adult Patients: Metaplasia or Vestigeal Remnants?

Handra-Luca

2016

International Surgery

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“…In cytological as well as histological preparations, benign mesothelial cells can exhibit simple reactive changes, reactive atypia, and squamous metaplasia; these morphological changes can pose diagnostic problems. [1][2][3][4] The application of immunohistochemical markers have proved very useful in effusion cytology. 1,2,[5][6][7][8][9][10][11] The anti-mesothelial antibody, HBME-1, has been shown to react to normal mesothelium, bronchial and endocervical epithelium, cartilage, and their malignant counterparts.…”

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confidence: 99%

Mesothelial hyperplasia with reactive atypia: Diagnostic pitfalls and role of immunohistochemical studies?a case report

Lee

Baloch

et al. 2000

Diagn. Cytopathol.

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The cytomorphologic features of highly reactive mesothelial cells can be difficult to distinguish from malignant cells. We report on an unusual case of mesothelial hyperplasia in a pericardial effusion. The specimen contained bizarre‐shaped cells and large tissue fragments in a patient with a history of lung carcinoma. The atypical cells were negative for CEA and LeuM‐1 and positive for cytokeratins (AE1/3) and HBME‐1. Strong HBME‐1 positivity supported a mesothelial origin of the atypical cells and led to the diagnosis of reactive mesothelium. While HBME‐1 cannot be used as the sole marker to establish an mesothelial origin; its use in a immunohistochemistry panel may be useful in individual cases to distinguish reactive mesothelial cells from carcinoma in effusion cytology. Diagn. Cytopathol. 2000;22:113–116. © 2000 Wiley‐Liss, Inc.

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“…In women, metaplasia of the peritoneum toward Müllerian-type epithelium is observed with some frequency. 7 In contrast, squamous metaplasia of the peritoneal or pleural surface is uncommon in humans and limited to single case reports, 3,6,7 most of them being incidental findings after laparotomy for other reasons, e.g., acute appendicitis, or to areas within cystic mesotheliomas. 8 In this report, squamous metaplasia of the pulmonary pleura in a horse is described in a case with chronic pulmonary disease.…”

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confidence: 99%

Multifocal Pleural Cystic Squamous Metaplasia in a Horse with Chronic Obstructive Bronchopneumonia

Baum¹,

Hewicker‐Trautwein²,

Wohlsein³

2004

Vet Pathol

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Abstract.A 10-year-old Knabstrupper stallion was euthanatized because of severe dyspnea and exercise intolerance. Postmortem examination revealed diffuse severe alveolar emphysema and chronic fibrosing pleuritis of the caudal lung. Parts of both caudal lung lobes were covered with multiple raised firm gray to yellow plaques. Histologically, these areas consisted of circumscribed pleural fibroses and cysts of metaplastic keratinizing squamous epithelium. Immunohistochemistry revealed intense labeling for cytokeratins 5/6 and 10. In addition, caudal lung lobes were severely affected by a chronic partially obliterative bronchiolitis and peribronchiolitis with multifocal pleural involvement.

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Squamous metaplasia of the peritoneum

Cited by 47 publications

References 9 publications

Acute Appendicitis and Periappendicitis Revealing Squamous and Transitional Cystic and Solid Nests in Adult Patients: Metaplasia or Vestigeal Remnants?

Acute Appendicitis and Periappendicitis Revealing Squamous and Transitional Cystic and Solid Nests in Adult Patients: Metaplasia or Vestigeal Remnants?

Mesothelial hyperplasia with reactive atypia: Diagnostic pitfalls and role of immunohistochemical studies?a case report

Multifocal Pleural Cystic Squamous Metaplasia in a Horse with Chronic Obstructive Bronchopneumonia

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