Squamous cell carcinoma presenting as a giant cutaneous horn of the lower lip

Popadić, Mirjana

doi:10.4103/0378-6323.125469

Cited by 9 publications

(6 citation statements)

References 5 publications

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“…Giant cutaneous horns of lip are comparatively rarer and malignancies associated with them are even more uncommon. On review of the literature, 9 cases in the past have been reported to have cutaneous horn over the lip and three of these had an associated squamous cell carcinoma at its base [ 7 – 9 ]. The important issue is not the horn itself which is dead keratin, but rather the underlying condition, which may be benign (seborrheic keratosis, viral warts, histiocytoma, inverted follicular keratosis, verrucous epidermal nevus, and molluscum contagiosum), premalignant (solar keratosis, arsenical keratosis, and Bowen's disease), or malignant (squamous cell carcinoma, rarely, basal cell carcinoma, metastatic renal carcinoma, granular cell tumor, sebaceous carcinoma, or Kaposi's sarcoma) [ 10 ].…”

Section: Discussionmentioning

confidence: 99%

Carcinoma Buccal Mucosa Underlying a Giant Cutaneous Horn: A Case Report and Review of the Literature

Kumar

Bijalwan²,

Saini³

2014

Case Reports in Oncological Medicine

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Cutaneous horn is a conical, dense, and hyperkeratotic protrusion that often appears similar to the horn of an animal. Giant cutaneous horns are rare; no incidence or prevalence has been reported. The significance of cutaneous horns is that they occur in association with, or as a response to, a wide variety of underlying benign, premalignant, and malignant cutaneous diseases. A case of giant cutaneous horn of left oral commissure along with carcinoma left buccal mucosa is reported here as an extremely rare oral/perioral pathology.

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Section: Discussionmentioning

confidence: 99%

Carcinoma Buccal Mucosa Underlying a Giant Cutaneous Horn: A Case Report and Review of the Literature

Kumar

Bijalwan²,

Saini³

2014

Case Reports in Oncological Medicine

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“…or malignant (squamous cell carcinoma, basal cell carcinoma, melanoma, Bowen's disease, Kaposi sarcoma etc.). 13 Malignancy in penile cutaneous horn has also been reported. 14 Most reports mention squamous cell carcinomas to be the malignant entity when found, whereas basal cell carcinoma, as was found in our case, is a very unusual occurrence with cutaneous horns.…”

Section: Discussionmentioning

confidence: 95%

“…8 Making a clinical diagnosis of the pathology at the base of the horn is usually difficult due to the obstructive nature of the horn and lack of other finding. 13 Therefore, to obtain an appropriate histopathological diagnosis, this lesion should undergo biopsy at the base of the horn, and for smaller lesions excision is advocated. 8 The underlying lesion may be benign (seborrheic keratosis, lichen simplex, pyogenic granuloma, benign nevus etc.…”

Section: Discussionmentioning

confidence: 99%

Cutaneous horn in a sun-protected site harbouring unusual malignancy

Ramji

2019

Int Surg J

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Cutaneous horns are conical, circumscribed projections formed by desquamation and layering of keratin. Although they can appear on the skin anywhere on the body, they are most commonly seen on the sun-exposed surfaces, and are often associated with solar keratosis. Cutaneous horns are most often benign, however they are a potential site of malignancy and may harbor premalignant or malignant lesions, the most common being squamous cell carcinoma, the causal relationship being straightforward and both squamous cell carcinoma and cutaneous horns can be equated with the common epithelial maker keratin. Other histological types of malignancies are not usually noted in conjunction with cutaneous horns. Here we describe a patient with a cutaneous horn over the volar aspect of the right forearm, a sun-protected site, harboring basal cell carcinoma, an infrequent finding.

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“…3 Among these four cases had presented with underlying malignancy. [7][8][9] Cutaneous horn presents like a thick, firm, elongated structure with a length of few millimetres to several centimetres from skin. It may be conical, cylindrical, curved or twisted in shape.…”

Section: Discussionmentioning

confidence: 99%

A giant cutaneous horn of oral commissure: a case report

et al. 2021

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Cutaneous horn is a conical, circumscribed, dense hyperkeratotic protrusion from skin with epithelial cornification. It is also known by the Latin name ‘Cornu cutaneum’. This rare medical entity resembles animal horn but histological disparity is present between both. They are more commonly present in sun exposed sites or areas that are prone for actinic radiation, burns and hence frequently seen in forearm and upper part of face. Only few cases have been reported with cutaneous horns in unusual sites. Cutaneous horns occurring in oral cavity or perioral regions are extremely rare. The significance of knowing about this dead keratinous cutaneous horn is that it may occur as a part of or in association with a wide range of underlying pathologies, either malignant, premalignant or benign. Majority are due to benign pathologies. We report an unusual presentation of cutaneous horn in left oral commissure of a 45-year-old gentleman which is an extremely rare perioral location for such an ailment.

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Squamous cell carcinoma presenting as a giant cutaneous horn of the lower lip

Cited by 9 publications

References 5 publications

Carcinoma Buccal Mucosa Underlying a Giant Cutaneous Horn: A Case Report and Review of the Literature

Carcinoma Buccal Mucosa Underlying a Giant Cutaneous Horn: A Case Report and Review of the Literature

Cutaneous horn in a sun-protected site harbouring unusual malignancy

A giant cutaneous horn of oral commissure: a case report

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