Squamous Cell Carcinoma of the Scalp After Radiotherapy for Tinea Capitis

Ronel, Daniel N.; Schwager, Robert G.; Avram, Marc R.

doi:10.1111/j.1524-4725.2004.30123.x

Cited by 7 publications

(4 citation statements)

References 16 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Late sequelae induced by radiation therapy include sclerosis and atrophy of skin and subcutaneous tissue (chronic radioder-matitis) and the development of nonmelanoma skin cancers. [1][2][3][4][5][6] The occurrence of malignant melanoma in skin areas exposed to ionizing radiations has been rarely reported. 7,8 The carcinogenetic potential of ionizing radiations on melanocytes is still unknown.…”

Section: Discussionmentioning

confidence: 99%

Melanocytic Nevus with Atypical Dermoscopic Features at the Site of Radiodermatitis

Arpaia¹,

Cassano²,

Veña³

2008

Dermatologic Surgery

View full text Add to dashboard Cite

show abstract

Section: Discussionmentioning

confidence: 99%

Melanocytic Nevus with Atypical Dermoscopic Features at the Site of Radiodermatitis

Arpaia¹,

Cassano²,

Veña³

2008

Dermatologic Surgery

View full text Add to dashboard Cite

show abstract

“…It should be kept in mind that radiation therapy does have the potential for adverse effects, including carcinogenesis, as described using the Keinbock-Adamson method for the treatment of tinea capitis. 19,20 However, in cases of very severe, refractory dissecting cellulitis, this small risk may be outweighed by the physical agony and emotional anguish of the disease itself. Also, the chronic cicatricial inflammation of the disease itself can predispose patients to squamous cell carcinoma regardless of treatment.…”

Section: Discussionmentioning

confidence: 99%

Modern external beam radiation therapy for refractory dissecting cellulitis of the scalp

et al. 2005

View full text Add to dashboard Cite

show abstract

“…In our study, 21.6% of patients had a history of exposure to X-ray for treating tenia capitis and the minimum duration between exposure to radiation and development of cancer was 50 years. It was reported that 200000 children were treated by this therapeutic protocol in the United States between 1930 and 1950 and further follow-ups were indicative of at least a fourfold rise in the prevalence of NMSC in these people, compared to other unexposed members of the public, and that the prevalence of BCC in these individuals was higher than SCC (19). Previous studies have shown that patients with chronic radio dermatitis characterized by atrophy of the skin, skin pigmentation disorders, and xerosis are more susceptible to cancer development; a finding consistent with the data found in the present study (15).…”

Section: Discussionmentioning

confidence: 99%

Epidemiological Study of Non-Melanoma Skin Cancers Qazvin Province, Iran

Beheshtiroy¹,

Hajmanoochehri²

2014

Biotech Health Sci

View full text Add to dashboard Cite

Background: Non-melanoma skin cancers (NMSC) are the most common cancers worldwide. These cancers are not accompanied by high mortality however they lead to various complications. Evaluation of NMSC predisposing factors could result in preventive measures, improvement of quality of life and reduction of medical costs. Objectives: This study aimed to determine predisposing factors of non-melanoma skin cancers in the province of Qazvin (Iran). Materials and Methods: A total of 484 proven cases of NMSC were evaluated for demographic characteristics, clinical findings, pathological type, location of lesion, and the existence of known or possible predisposing factors such as skin type, exposure to sunlight, and family and drug history within a ten-year period from 2001 to 2011. Data were recorded in a questionnaire through interview and clinical examination of patients by a physician and a dermatologist, respectively. Data were analyzed using the SPSS version 16 software and statistical tests including t-test and chi-square tests. Results: Of the 484 patients, 294 (60.7%) were male and 190 (39.3%) were female. Most cases of carcinoma were found in basal cells (77.7%) and the rest of squamous cells. The most common sites of involvement were the head and scalp. The most frequent predisposing factors were working in the open air (70.7%), history of previous radiation for treatment of tenia capitis (26.1%), and chronic skin diseases such as burn eschar, chronic lesion, fistula and actinic keratosis (35.7%). The most prevalent Fitzpatrick skin phenotypes were II or III (75.4%). There were significant correlations between the incidence of NMSC and hookah smoking and oral contraceptive pill (OCP) consumption. Conclusions: Skin phenotypes II and III were the most common types found in the present study and this could be due to the higher frequency of these phenotypes among the study population. The lower incidence of NMSC in areas other than the neck and scalp could be associated with the importance of covering style used by the population under study. Known risk factors for the incidence of NMSC were also observed in the present study. A history of radiotherapy for treatment of tenia capitis was observed in a considerable percentage of patients, which could lead to the incidence of cancer several decades later. Further studies are needed to determine the role of hookah smoking and the use of OCP in the occurrence of NMSC.

show abstract

Squamous Cell Carcinoma of the Scalp After Radiotherapy for Tinea Capitis

Cited by 7 publications

References 16 publications

Melanocytic Nevus with Atypical Dermoscopic Features at the Site of Radiodermatitis

Melanocytic Nevus with Atypical Dermoscopic Features at the Site of Radiodermatitis

Modern external beam radiation therapy for refractory dissecting cellulitis of the scalp

Epidemiological Study of Non-Melanoma Skin Cancers Qazvin Province, Iran

Contact Info

Product

Resources

About