SQUAMOUS CELL CARCINOMA OF THE LIP: A RETROSPECTIVE REVIEW OF THE PETER M <scp>AC</scp>CALLUM CANCER INSTITUTE EXPERIENCE 1979–88

McCombe, David; MacGill, Kirstie; Ainslie, Jill; Beresford, J.; Matthews, Jane P.

doi:10.1046/j.1440-1622.2000.01827.x

Cited by 46 publications

(44 citation statements)

References 19 publications

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“…The predominant treatment used elsewhere has been reported to be a combination of surgery and radiotherapy. 7,10,12 In the current study the treatment of lip cancers (69.2 per cent) and floor of mouth cancers (52.9 per cent) was by surgery and radiotherapy, whereas for tongue cancers the predominant treatment was chemotherapy and radiotherapy (36.1 per cent). This possibly reflects the severity of disease present in the patients of this tertiary referral clinic.…”

Section: Discussionmentioning

confidence: 56%

Oral cancer at a Tasmanian tertiary referral clinic, The Royal Hobart Hospital 1996–2002

2005

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Background:The Holman Clinic at the Royal Hobart Hospital includes a multi-disciplinary head and neck clinic which functions as a tertiary referral centre for Southern Tasmania and involves Ear Nose and Throat surgeons, Oral and Maxillofacial Surgeons, Plastic and Reconstructive Surgeons, Radiation Oncologists and Medical Oncologists. Methods: The aim of this study was to examine retrospectively the number, gender distribution, age, site of lesion, histology, mortality and treatment modalities of the oral cancers referred to the Holman clinic at the Royal Hobart Hospital. The medical histories and a database of the Holman clinic were used as the sources of data for this study. A total of 101 patients were treated for oral cancer in the Holman clinic at the Royal Hobart Hospital from 1996 to 2002. There were 64 males and 37 females. Results: The distribution of anatomical sites of the oral cancers in this study was as follows: 36 oral tongue lesions, 17 floor of mouth, 13 lip, five retromolar trigone, five mandibular alveolus, six buccal mucosa, nine palatal and 10 minor and major salivary gland cancers. The most common site of oral cancer was the tongue (35.6 per cent), followed by the floor of mouth (16.8 per cent) and lip (12.9 per cent). Conclusions:The majority of oral cancers were squamous cell carcinoma, except for the salivary gland cancers. The incidence of squamous cell carcinoma was between 67 and 100 per cent, depending upon the site involved. The trends found in this study are similar to those previously documented over the past 20 years.

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Section: Discussionmentioning

confidence: 56%

Oral cancer at a Tasmanian tertiary referral clinic, The Royal Hobart Hospital 1996–2002

2005

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“…3, 41 The short-and long-term side effects of radiation therapy can be considerable, especially when sensitive areas are treated, such as the periocular region, the ear, or the lower leg or hand. Furthermore, radiation therapy of SCC in situ lesions located on the lower leg may be associated with high rates of poor/ failed healing (20%-25%).…”

Section: Radiation Therapymentioning

confidence: 99%

Non-melanoma Skin Cancer in Canada Chapter 5: Management of Squamous Cell Carcinoma

et al. 2015

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Background Squamous cell carcinoma (SCC) is the second-most common form of non-melanoma skin cancer (NMSC). Objective To provide guidance to Canadian health care practitioners regarding management of SCCs. Methods Literature searches and development of graded recommendations were carried out as discussed in the accompanying introduction (chapter 1 of the NMSC guidelines). Results SCCs are sometimes confined to the epidermis, but they can also invade nearby tissues and, in some cases, metastasize to neighbouring lymph nodes or other organs. This chapter discusses the natural history, staging, prognosis, and management of SCC—a tumour type that is less common but typically more aggressive than BCC. For this reason, margin control is strongly preferred in treating SCCs. Conclusions Although approaches such as cryosurgery and radiation therapy may be considered for some patients, surgical excision—sometimes coupled with radiation—remains the cornerstone of SCC management. Patients with high-risk SCC may also be considered for referral to an appropriate multidisciplinary clinic.

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“…In a series of 232 cases of K McCombe [23], the local recurrence occurred in 7.6% of patients, while regional metastases developed in 4.3% of patients when the treatment undertaken was surgery. The survival rate at 5 years is above 85% for the majority of the authors and can reach 98% [13,24].…”

Section: Discussionmentioning

confidence: 99%

Lip Cancer: Epidemiologic, Clinical, Evolutive, and Therapeutical Aspects

Rafik¹,

Taquafi²,

H³

et al. 2015

Journal of Cancer Science and Clinical Oncology

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SQUAMOUS CELL CARCINOMA OF THE LIP: A RETROSPECTIVE REVIEW OF THE PETER M ACCALLUM CANCER INSTITUTE EXPERIENCE 1979–88

Cited by 46 publications

References 19 publications

Oral cancer at a Tasmanian tertiary referral clinic, The Royal Hobart Hospital 1996–2002

Oral cancer at a Tasmanian tertiary referral clinic, The Royal Hobart Hospital 1996–2002

Non-melanoma Skin Cancer in Canada Chapter 5: Management of Squamous Cell Carcinoma

Lip Cancer: Epidemiologic, Clinical, Evolutive, and Therapeutical Aspects

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