Squamous cell carcinoma of the gingiva

Gingival squamous cell carcinoma masquerading as an aphthous ulcer

“…[111213] There is a need to document GSCC as a separate entity as it exhibits features different from general OSCC. These include its direct invasion of the bone,[14] its predilection for females unlike OSCC which is generally seen in males[3] and the least association with the classic risk factors of tobacco and alcohol consumption. [6] The fact that it resembles periodontal disease[15] or an endo-perio lesion[14] or an ulcer as in the present case may make it go unnoticed by a complacent or casual examiner.…”

“…[2] Gingival SCC (GSCC) is an uncommon condition with a likely predilection for females. [3] It clinically presents as an exophytic mass with a granular, papillary, or verrucous surface or as an ulcerative lesion. [4]…”

“…[5] It typically arises from the keratinized mucosa, commonly in a posterior site destroying the underlying alveolar bone leading to tooth mobility. [6] Unlike tobacco and alcohol consumption, which are significant risk factors for OSCC,[3] GSCC is weakly or least associated with them. [6] It is generally agreed that GSCC is more common in the mandible than the maxilla[7] and 60% of those are located posterior to premolars.…”

Gingival Squamous Cell Carcinoma Mimicking a Dentoalveolar Abscess: Report of a Case

“…The aggressive behavior may relate to its degree of differentiation. Poorly differentiated oral SCC is uncommon (3,25,26) but more likely to have early cervical metastasis (23,27). Surgery, including excision of primary tumor and neck dissection, is the major treatment modality for gingival SCCs.…”

Gingival squamous cell carcinoma presenting as periodontal lesion in the mandibular posterior region

“…Gingival squamous cell carcinoma (GSCC) is an infrequent oral tumour 1 – 3. It represents less than 10% of diagnosed intraoral carcinoma 4.…”