“…( Bogani et al, 2014 , Murhekar et al, 2008 , Patton et al, 1962 ) Though some hypothesize a shared pathway with cervical cancer, there is limited data to support this. ( Bogani et al, 2014 , Goodman et al, 1996 , Wu et al, 2018 , Thomakos et al, 2008 , Katoaka et al, 1997 ) Notably, many risk factors associated with endometrioid adenocarcinoma of the uterus, such as obesity and hyperestrogenism, do not appear to correlate with PESCC. ( Goodman et al, 1996 ) Published reports consistently agree that age is a significant risk factor for the development of PESCC, with the average age of diagnosis 65 years old or above.…”