SQUAMOUS CELL CARCINOMA IN TWO SNOW LEOPARDS (UNCIA UNCIA) WITH UNUSUAL AURICULAR PRESENTATION

Abstract

Squamous cell carcinoma (SCC) is well documented in snow leopards ( Uncia uncia ) and most common locations are oral, facial, or pedal. These two cases illustrate an unusual auricular presentation, which is more often reported in white domestic cats. The animals were aged and presented clinical signs of otitis such as head shaking and ear scratching. Clinical examinations showed auricular canal masses with chronic purulent otitis. In both cases, clinical deterioration led to euthanasia and histology of the ear canal was consistent with SCC and showed numerous vascular emboli. These cases illustrate an unreported aggressive localization for SCC in snow leopards, which should be included in the differential diagnosis of otitis in this species. Auricular SCC may be underdiagnosed as the ear canal is infrequently sampled for histopathology. This auricular localization should be considered when metastases are found upon necropsy without internal primary tumor.

An Overview of Neoplasia in Captive Wild Felids in Southern Italy Zoos

“…An oral SCC was observed in a female lion; SCC is the most common oral neoplasm in domestic cats ( 22 ). Although the most frequent site of SCC in non-domestic animals is the skin ( 9 , 23 – 25 ), oral squamous cell carcinoma has been recently reported in captive felids ( 26 – 29 ). Cutaneous SCCs are associated with prolonged exposure to ultraviolet light, lack of pigment in the epidermis, lack of hair, and infection with Felis catus papillomavirus type-2 (FcaPV-2) ( 22 ).…”

Meibomian Gland Adenocarcinoma in a Captive Indian Leopard (Panthera pardus fusca)

“…ISSN : 2572-6579 2 Mathews Journal of Veterinary Science https://doi.org/10.30654/MJVS.10014 Neoplastic developments have been observed in Indian leopards, the cases reported include squamous cell carcinoma by [3,4] (Quintard et al, 2017, Kesdangsakonwut et al, 2014, mammary gland adenoma [5] (Nakamura et al, 2018), thyroid carcinoma [6], skin lipoma [7] (Baquir et al, 2014), benign gastric neuroendocrine tumor [8] (Dobson et al, 2013), and uterine leiomyoma [9] (Willott et al, 2005). Some novel neoplastic incidences like cystic trichoblastoma, pheochromocytoma, meningioma, and bronchiolar adenoma were also reported in leopards.…”