Squamous cell carcinoma associated with lupus vulgaris

Abstract

Squamous cell carcinomas are known to arise in certain chronic, scarring dermatoses and also to be associated with exposure to ultraviolet radiation. We now report a case arising in a plaque of lupus vulgaris, the patient having received radiation from a Finsen lamp as a child for a tuberculous abscess in that region.

Cutaneous tuberculosis: epidemiologic, etiopathogenic and clinical aspects - Part I

“…19,22,23 The incidence of malignant transformation into squamous cell carcinoma in LV plates ranged from 0.5 to 10.5% and it usually occurs after 25-30 years of untreated disease. 36,37 The development of other malignancies, such as basal cell carcinoma has also been reported. 20 …”

Lupus Vulgaris: A New Look at an Old Symptom – The Lupoma Observed with Dermoscopy

“…A correct diagnosis and an adequate treatment are crucial because LV, if left untreated, carries the risk of local destruction or development of malignant skin tumors including squamous cell carcinoma and, less commonly, basal cell carcinoma and cutaneous sarcoma [6][7][8][9][10] . Dermoscopy is a noninvasive diagnostic tool allowing the visualization of pigmented and vascular structures that are not visible to the unaided eye [11] .…”

Cutaneous squamous cell carcinoma developing in lupus vulgaris exfoliativus persistent for 40 years

“…This occurs mostly in patients in their fourth and fifth decades. Usually it takes about 25–30 years to develop a carcinoma within a plaque of lupus vulgaris 5,8–10 . In our patient the malignancy was diagnosed at the age of 63 years, after at least 38 years from the onset of lupus vulgaris.…”

“…The extent of cutaneous LV spread depends upon the duration of the tuberculosis and the patient's cell‐mediated immunity. Squamous cell carcinoma (SCC) can develop within long lasting plaques 4,5 …”