Squamous cell carcinoma as a long-term effect after skin vascular malformation radiotherapy

Abstract

A b s t r a c tIn the past, vascular anomalies were divided into vascular malformations and vascular tumors. Radiotherapy was one of the leading methods of treatment for vascular malformations and infantile haemangiomas in the past and considered as harmless in those days. Many years later it turned out that management was not necessary and dangerous, even responsible for possible skin cancers appeared within areas exposed to radiotherapy in the future. The case report shows the presence of squamous cell carcinoma within the irradiated vascular malformation of the frontotemporal area in early childhood. The lesion was surgically removed, the defect was covered by split thickness skin graft. The histopathological evaluation confirmed the carcinoma as well as its complete resection. Assessing the adult patients with vascular anomaly one should be aware of possible radiation therapy for that malformation in the past, then the evaluation of the skin must be careful and focused on possible neoplasmatic lesions. K Ke ey y w wo or rd ds s: : radiotherapy, vascular malformations, squamous cell carcinoma.

Analysis of selected recurrence risk factors after treatment of head and neck basal cell carcinoma

“…Other risk factors include radiotherapy and immunosuppression (risk being 10 to 20 times higher in patients after organ transplants) [6–9]. …”

“…Eighty-five percent of BCC cases are located on the skin of the head and neck [ 4 ], which results from the exposure to UV sunshine, the main risk factor [ 5 ]. Other risk factors include radiotherapy and immunosuppression (risk being 10 to 20 times higher in patients after organ transplants) [ 6 – 9 ].…”