Squamous Cell Carcinoma Arising on an Epidermal Inclusion Cyst: A Case Presentation and Review of the Literature

Antón-Badiola, I.; Miguel-Fraile, Pilar San; Peteiro-Cancelo, A.; Ortiz-Rey, J.A.

doi:10.1016/s1578-2190(10)70646-6

Cited by 21 publications

(23 citation statements)

References 6 publications

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“…It is im-portant to distinguish a cyst with malignant change versus a cystic squamous carcinoma. A cystic squamous cell carcinoma shows a direct origin from epidermis whereas a malignant lesion arising in an epidermal cyst is confined only to the cyst wall [2]. In our case, the skin and hence epidermis was not involved by the tumour.…”

Section: Discussionmentioning

confidence: 49%

“…The typical locations include the head and neck (42.1% of cases), followed by the trunk and legs [2]. However, malignant transformation of an epidermal cyst of breast is a rare event.…”

Section: Discussionmentioning

confidence: 99%

“…Although malignant transformation should be suspected in large epidermal cysts with rapid growth, ulceration, fistulization and local recurrence [2], cases of squamous cell carcinoma arising in a clinically benign cyst having a normal gross appearance have been reported [5]. It is, therefore, recommended that all lesions presumed to be epidermal cysts should be completely excised and submitted intact for a detailed histological examination for potential carcinomatous changes.…”

Section: Discussionmentioning

confidence: 99%

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Squamous cell carcinoma arising in epidermal inclusion cyst of breast: A diagnostic dilemma

Suhani

Aggarwal

Meena

et al. 2015

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Section: Discussionmentioning

confidence: 49%

“…The typical locations include the head and neck (42.1% of cases), followed by the trunk and legs [2]. However, malignant transformation of an epidermal cyst of breast is a rare event.…”

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Squamous cell carcinoma arising in epidermal inclusion cyst of breast: A diagnostic dilemma

Suhani

Aggarwal

Meena

et al. 2015

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“…Malignant transformation of epidermal cysts into squamous cell carcinoma is rare. The incidence of malignant transformation ranges from 0.011 to 0.045% …”

Section: Discussionmentioning

confidence: 99%

Squamous cell carcinoma arising from a vulval epidermal cyst

Sze

Richmond

Bickers

et al. 2016

J of Obstet and Gynaecol

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Malignant transformation of epidermal cyst is rare, with most cases arising in the head and neck. Here, we report a case of squamous cell carcinoma arising from a longstanding epidermal cyst in the right vulva of a 65-year-old woman. The patient presented with a sudden increase in size of the cyst over 6 weeks to the size of a golf ball. Excisional biopsy and histology indicated moderately differentiated squamous cell carcinoma within an epidermal cyst (FIGO stage IB). Strong p16 immunopositivity was also demonstrated and the potential significance of this is discussed. Limited right hemivulvectomy and right groin node dissection were performed.

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“…It should be kept in mind that large epidermal inclusion cysts with ulceration, rapid growth, resistance to treatment, recurrence and fistula drainage might have malignant potential. Therefore, complete surgical excision and histopathological evaluation are mandatory to rule out malignancy (Antón-Badiola, San Miguel-Fraile, Peteiro-Cancelo & Ortiz-Rey, 2010;Baek, Kim, Jung, Sohn & Kwon, 2011). Hereby, we present a 48-year-old male with multiple epidermal inclusion cysts on the scalp treated surgically with squeeze technique.…”

Section: Introductionmentioning

confidence: 98%

Surgical Removal of the Epidermal Inclusion Cysts With Squeeze Technique: Case Report

Yüksel¹,

Tamer²

2015

EMHPJ

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Epidermal inclusion cysts are common benign cutaneous cysts which arise from hair follicles. These cysts usually present as asymptomatic, small, smooth, firm, round, slow growing swellings on hair bearing areas such as scalp, face, neck and trunk. Epidermal inclusion cysts are easily diagnosed by their clinical features. However, trichilemmal cyst, dermoid cyst, neurofibroma, hemangioma, lipoma and liposarcoma should also be kept in mind in differential diagnosis of cutaneous cystic lesions. As malignant transformation of epidermal inclusion cysts has been reported, histopathological evaluation of epidermal inclusion cysts is mandatory in order to rule out malignancy. Moreover, giant epidermal inclusion cysts with ulceration, rapid growth, resistance to treatment, recurrence and fistula drainage may have malignant potential. Therefore, epidermal cysts should be surgically removed. There are several different types of surgical techniques to remove cutaneous cysts. A proper surgical technique should facilitate the complete removal of the cyst wall to prevent recurrence. In addition, it should provide minimal scarring and a low wound infection rate. Epidermal inclusion cysts can be easily removed surgically with squeeze technique. In this technique, the cyst is squeezed out through a small incision using both index fingers. Thus, the cyst is not ruptured. The squeeze technique allows the cyst capsule to remain intact. Therefore, the risk of wound infection, recurrence and scar formation is minimized. Hereby, we present a 48-year-old male with multiple epidermal inclusion cysts on the scalp treated surgically with squeeze technique.

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Squamous Cell Carcinoma Arising on an Epidermal Inclusion Cyst: A Case Presentation and Review of the Literature

Cited by 21 publications

References 6 publications

Squamous cell carcinoma arising in epidermal inclusion cyst of breast: A diagnostic dilemma

Squamous cell carcinoma arising in epidermal inclusion cyst of breast: A diagnostic dilemma

Squamous cell carcinoma arising from a vulval epidermal cyst

Surgical Removal of the Epidermal Inclusion Cysts With Squeeze Technique: Case Report

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