Squamous Cell Carcinoma arising in a Giant Epidermal Cyst: a Case Report

Abstract

Epidermal cysts are commonly encountered in surgical practice. Malignant degeneration of epidermal sebaceous cyst is uncommon. The authors report the case of a 38-year Filipino woman presenting with a voluminous sebaceous cyst of the left buttock. Ultrasonography and computer tomography were made preoperatively without any hint of eventual malignant degeneration. Marginal excision was performed with direct closure of the skin. The histological examination revealed epidermal sebaceous cyst with squamous cell carcinoma in situ, which is a quite rare, but well known complication occurring in sebaceous cysts.

Keratinous cysts: with body site distribution, size and the types of the cysts

“…Golden ve Zide çalışmalarında %79 gibi bir oranla en sık EİK saptamış ve bu kistlerin vücutta tüm lokalizasyonlarda görülebileceklerini vurgulamışlardır 8 . EİK'lerinde malin dönüşüm oldukça nadir de olsa bildirilmiştir 10 . EİK etyolojisinde konjenital nedenler ve travma suçlanmaktadır 11 .…”

Giant epidermal cyst of the gluteal region

“…5,6 There is risk of malignant transformation of the sebaceous cyst. 7,8 Squamous cell carcinoma, Basal cell carcinoma, Mycosis fungoides and melanoma are the various types of malignancies reported in literature. 9,10 Diagnosis is generally achieved by FNAC.MRI is an useful adjunct to establish the diagnosis in atypical locations.…”

Trichilemmal Cyst Over Scalp: An Uncommon Case Report

“…In our patient there were no different sores exhibit somewhere else amid the examination. Various sorts of threat that can emerge from a huge sebaceous growth are squamous cell carcinoma, basal cell carcinoma, mycosis fungicides and melanoma in long standing cases in elderly [8][9][10]. Differential diagnosis if this type swelling is osteomyelitis with complication, potts pufy tumor, mycosis fungoid.…”