Squamous Cell Carcinoma Arising From a Fibroepithelial Polyp

Abstract

Fibroepithelial polyps (FEPs) are among the most common benign skin lesions treated frequently without submitting for histologic examination since malignant degeneration is exceedingly rare. In this case report, we describe an aggressive gross squamous cell carcinoma mass arising from a large pedunculated-type FEP located at the lower limb, which, to our knowledge, has not been reported yet.

An Unusually Massive Fibrous Epulis Observed with Bone Resorption on the Maxillary Anterior Region: Case Report

“…Ancak malign dönüşüm riskinin yüksek olması hâlinde (uzun süreli kronik irritasyon ve inflamasyon) histopatolojik incelemenin gerekli olduğunu savunan birçok araştırma mevcuttur. 11,13,14 Olgumuzda lezyonun büyük olması ve malign dejenerasyon riskinin bilinmemesi nedeni ile ana kitle histopatolojik incelemeye gön-derilmiştir.…”

Giant fibroepithelial polyp of the glans penis not associated with condom-catheter Use: A case report and literature review

“…18 Similarly, a case of urothelial carcinoma has been reported in a ureteral FEP. 19 Although our case showed no evidence of dysplasia or malignancy, we would advise careful sampling and examination of these lesions to exclude a primary malignancy or malignancy arising in the setting of a FEP.…”

Pedunculated hemangiopericytoma‐like tumor: peculiar fibroepithelial polyp or fibrous histiocytoma variant

“…Dilated blood vessels are often present, frequently with a branching architecture. Only very rarely have malignancies been found to either arise within or mimic FEP 11–15 . As such, it has been debated as to whether or not these lesions should be submitted for histological examination 16 .…”

“…Only very rarely have malignancies been found to either arise within or mimic FEP. [11][12][13][14][15] As such, it has been debated as to whether or not these lesions should be submitted for histological examination. 16 Occasionally, however, the stroma possesses more complex features, including cellular foci and cytologic pleomorphism, expanding the differential diagnosis to include pseudosarcomatous polyp, pleomorphic fibroma, giant cell fibroblastoma (GCF), pleomorphic hyalinizing tumor and dermatofibrosarcoma protuberans (DFSP).…”