“…Yoo et al report in their current paper that there was a close relationship between activated eosinophils and the maximal response achieved during methacholine challenge in cough variant asthma, but not in their patients with classic asthma. Interestingly, in patients with allergic rhinitis without asthma, sputum eosinophilia was also related more closely to the maximal plateau response rather than to the PC 20 (17). It would be of interest to examine the airway response of patients with eosinophilic bronchitis presenting with cough, but with a normal PC 20 (18).…”