Sprint Exercise of Juvenile Animals Does Not Impact Cartilage Glycosaminoglycan or Synovial Fluid Neopeptide Collagenase Cleavage of Type I and II Collagen Content

Logan, Alyssa A.; Nielsen, B.D.; Manfredi, Jane M.; Robison, C.I.

doi:10.1016/j.jevs.2021.103405

Cited by 1 publication

(3 citation statements)

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“…The determination of GAG content in the proximal surface of MC III and IV was not different among treatments. It has been previously speculated that in 15-week-old calves, the joints may still be homogeneous and GAG content was not influenced by short-duration exercise [ 23 ]. In this study, within the small circle exercise group, the left (outside) leg had greater GAG content in the MC III and IV proximal surface compared to the right (inside) leg.…”

Section: Discussionmentioning

confidence: 99%

“…Glycosaminoglycans (GAG) are a hydrophilic proteoglycan in the extracellular matrix of articular cartilage, which provide shock absorption and resistance against forces [ 22 ]. Within articular cartilage, the GAG concentration had been found to be heterogenous between joint locations [ 22 , 23 ]. Biomarkers can be combined with the evaluation of bone morphology as well as tensile testing to determine the activity, shape, and strength of bone, as well as joint health [ 2 , 24 ].…”

Section: Introductionmentioning

confidence: 99%

“…The objective of this study was to utilize a calf model to determine the impact of diameter during circular exercise at the walk to forelimb bone and joint health in juvenile animals. Calves have been used as a model for the management and exercise of young horses successfully in previous studies [ 2 , 23 , 24 , 25 ]. It was hypothesized that exercise on a smaller diameter circle would lead to increased biological markers of joint inflammation and metabolism and greater asymmetry between inside and outside forelimbs.…”

Section: Introductionmentioning

confidence: 99%

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The Impact of Circular Exercise Diameter on Bone and Joint Health of Juvenile Animals

Logan

Nielsen

Hiney

et al. 2022

Animals

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Circular exercise is used in many equestrian disciplines and this study aimed to determine if circle diameter impacts juvenile animal forelimb bone and joint health. On day 0, 24 calves at 9 weeks of age were assigned the following exercise treatments: small circle (12 m clockwise), large circle (18-m clockwise), treadmill, or non-exercised control. Exercise was initiated at 1.1–1.5 m/s for 5 min/d and increased 5 min weekly until reaching 30 min/d. On day 49, synovial fluid was collected from multiple joints, cartilage was collected from the proximal surface of fused third and fourth metacarpi (MC III and IV), and forelimbs underwent computed tomography scans. A statistical analysis (PROC mixed) was performed in SAS 9.4. The inside leg of the small circle treatment had a larger MC III and IV dorsopalmar external diameter than the outside (p = 0.05). The medial proximal phalanx had a greater mediolateral diameter than the lateral proximal phalanx of the small circle treatment (p = 0.01). Fetlock nitric oxide was greater in the large circle and treadmill treatments (p < 0.0001). Cartilage glycosaminoglycan concentration was greater in the outside leg of the small circle exercise treatment than the inside leg (p = 0.03). Even at slow speeds, circular exercise diameter can impact joint and bone health, but faster speeds may have greater alterations.

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Section: Discussionmentioning

confidence: 99%