2022
DOI: 10.1016/j.rvsc.2022.04.014
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Spray-drying-microencapsulated Minthostachys verticillata essential oil and limonene as innovative adjuvant strategy to bovine mastitis vaccines

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Cited by 8 publications
(3 citation statements)
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“…Various reasons may contribute to the failure of traditional vaccine, such as poor immunogenicity of the antigen ( Rainard et al, 2022b ), the lack of a suitable drug delivery system ( Wang K. et al, 2022 ), the effect of immune inductive sites ( Rainard et al, 2022a ), and errors due to manual operation. In recent years, differing from previous vaccine strategies that were based on biological carriers such as engineered bacteria or adenovirus ( Lasaro and Ertl, 2009 ), or specific antigens combined with immune adjuvants ( Liu et al, 2021 ; Campra et al, 2022 ), a new vaccine development platform based on nucleic acid [DNA ( Vogel and Sarver, 1995 ) or RNA ( Geall et al, 2013 )] has emerged. Nucleic acid vaccines have been introduced as the third generation vaccines with the advantage that they are more prominent in inducing humoral immunity or cellular immunity and can provide better protection compared to traditional vaccines ( Wadman, 2021 ).…”
Section: Emerging Applications Of Noncoding Rnas In Mastitismentioning
confidence: 99%
“…Various reasons may contribute to the failure of traditional vaccine, such as poor immunogenicity of the antigen ( Rainard et al, 2022b ), the lack of a suitable drug delivery system ( Wang K. et al, 2022 ), the effect of immune inductive sites ( Rainard et al, 2022a ), and errors due to manual operation. In recent years, differing from previous vaccine strategies that were based on biological carriers such as engineered bacteria or adenovirus ( Lasaro and Ertl, 2009 ), or specific antigens combined with immune adjuvants ( Liu et al, 2021 ; Campra et al, 2022 ), a new vaccine development platform based on nucleic acid [DNA ( Vogel and Sarver, 1995 ) or RNA ( Geall et al, 2013 )] has emerged. Nucleic acid vaccines have been introduced as the third generation vaccines with the advantage that they are more prominent in inducing humoral immunity or cellular immunity and can provide better protection compared to traditional vaccines ( Wadman, 2021 ).…”
Section: Emerging Applications Of Noncoding Rnas In Mastitismentioning
confidence: 99%
“…17,18 (−)-Limonene, a component of turpentine, is widely used in food, pharmaceuticals, cosmetics, etc. 19 It has anti-inflammatory, 20 antidiabetic, 21 antioxidant, 22 and anti-cancer 23 activities in medicine and has positive effects in the treatment of gastric ulcers 24 and asthma. 25 Limonene can also be used as mercury absorbers by forming polymers with sulfur.…”
Section: Introductionmentioning
confidence: 99%
“…α-Pinene, the most abundant component of turpentine, can promote apoptosis, and its derivatives have the potential to be used as lead compounds for the development of hepatocellular carcinoma drugs. , Pine trees themselves can secrete metabolites (such as α-pinene) to defend against the wilt disease caused by pine wood nematodes. , In addition, camphene and limonene with higher added values can be derived by the isomerization of α-pinene. , (−)-Limonene, a component of turpentine, is widely used in food, pharmaceuticals, cosmetics, etc . It has anti-inflammatory, anti-diabetic, antioxidant, and anti-cancer activities in medicine and has positive effects in the treatment of gastric ulcers and asthma . Limonene can also be used as mercury absorbers by forming polymers with sulfur .…”
Section: Introductionmentioning
confidence: 99%