Spray drying conditions and encapsulating composition effects on formation and properties of sodium diclofenac microparticles

Optimization of Sour Cherry Juice Spray Drying as Affected by Carrier Material and Temperature

“…This is one of the most important indicators of spray drying eff ectiveness and fi nal product quality (28).…”

Spray drying of liquorice (Glycyrrhiza glabra) extract

“…Thus, powders with less moisture content were formed. Osman and Endut (2009), Quek et al (2007), Rattes and Oliveira (2007), Goula and Adamopoulos (2010), Ersus and Yurdagel (2007), and Tonon et al (2008) also observed a reduction of powders moisture content with increasing air temperatures, studying the spray drying of roselle-pineapple juice, watermelon juice, sodium diclofenac, orange juice concentrate, black carrot and açai, respectively. An increase in solids in the feed reduces amount of free water for evaporation.…”

“…The moisture content was expressed in terms of the percent wet basis (% w.b.) as 100×kg water/kg wet material (Rattes and Oliveira 2007). Dublicate samples were analysed and the mean reading was recorded.…”

Investigation of a novel 3-fluid nozzle spray drying technology for the engineering of multifunctional layered microparticles

“…Numerous microencapsulation techniques have been developed over the years and these range from solvent evaporation from emulsions to coacervation-phase separation, coating of non-pareil beads and spray drying. Microencapsulation of pharmaceutical actives using spray drying is a well established method and the formulation and process parameters influencing microencapsulation have been studied extensively [2][3][4]. The spray drying process generally consists of atomizing the feed fluid through a nozzle to form fine droplets which are dried in a stream of hot drying air or nitrogen.…”

“…Considerable data have been published to date on the effect of process and formulation variables on the characteristics of the resultant microparticles [4,[13][14][15]. A change in the feed flow rate was reported to directly influence the particle size, and inversely influence the particle size distribution, particle morphology and product recovery [13].…”