SPR‐enhanced fluorescence and protein‐improved blood compatibility of quadruple core/shell nanostructure of Ag@SiO₂@Eu³⁺(tta)₃Phen@Protein

Abstract

This study presents a quadruple core/shell nanostructure of Ag@SiO 2 @Eu 3+ (tta) 3 Phen@Protein with both excellent fluorescent property and blood compatibility. Surface-plasma resonance (SPR) was utilised to enhance the fluorescence of europium (Eu 3+) complexes. In this situation, the fluorescence of Eu 3+ (tta) 3 Phen in the triple Ag@SiO 2 @Eu 3+ (tta) 3 Phen nanostructure is greatly enhanced. To increase the biocompatibility in blood, lysozyme was used to modify the surface of the above triple nanostructure to get the quadruple nanostructure of Ag@SiO 2 @Eu 3+ (tta) 3 Phen@lysozyme. Then, through the clinical anti-coagulation tests in human blood, the blood compatibility of Ag@SiO 2 @Eu 3+ (tta) 3 Phen@lysozyme is largely improved comparing with the triple nanostructure of Ag@SiO 2 @Eu 3+ (tta) 3 Phen, and the values of PT-S, APTT-S, TT-S, and AT-III of quadruple nanostructure blood sample with the modification of protein have the high correlation coefficients, 0.993-0.994, which means that the quadruple nanostructure of Ag@SiO 2 @Eu 3+ (tta) 3 Phen@lysozyme is close to the anti-coagulation property of physiological saline state (0.9% NaCl aqueous solution). Thus, this work provides two key properties of the quadruple nanostructure of Ag@SiO 2 @Eu 3+ (tta) 3 Phen@lysozyme: the excellent fluorescence and the outstanding blood compatibility. This nanomaterial can be applied to bio-imaging and bio-sensing in blood.

Using Dual Microresonant Cavity and Plasmonic Effects to Enhance the Photovoltaic Efficiency of Flexible Polymer Solar Cells

“…Implementing a highly efficient transparent conductive electrode (TCE) on polymer substrates is taken into account as a primary task to resolve the issue [5,[14][15][16][17][18][19][20][21]. Typical oxide-based TCEs, represented by indium tin oxide (ITO), in an amorphous phase exhibit seriously reduced electrical conductivity and optical transparency on the polymer substrates.…”