Spontaneous Splenic Rupture

Goldstone, Stephen E.; Gold, Michael S.

doi:10.1007/978-1-4899-0476-8_20

Cited by 1 publication

(6 citation statements)

References 14 publications

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“…However, a visible thrombus in the main splenic vein suggests acute thrombosis may have contributed to a sudden increase in intrasplenic pressure, causing a rupture in a weak spleen. 1 When the conservative treatment is chosen for the spontaneous splenic rupture because of metastasis, the mortality rate is reported to be as high as 100%. 1,8 The short-term prognosis of splenic rupture relates to the application of prompt surgical intervention, although the prognosis of the primary tumor determines life expectancy.…”

Section: Discussionmentioning

confidence: 99%

“…1 When the conservative treatment is chosen for the spontaneous splenic rupture because of metastasis, the mortality rate is reported to be as high as 100%. 1,8 The short-term prognosis of splenic rupture relates to the application of prompt surgical intervention, although the prognosis of the primary tumor determines life expectancy. 8 Both two obvious thromboses in the main splenic vein and the mid-cerebral artery may be related to hypercoagulability peculiar to cancer patients.…”

Section: Discussionmentioning

confidence: 99%

“…The absence of apparent infarction in pathological examination makes thromboembolism with subsequent infarction and rupture unlikely. However, a visible thrombus in the main splenic vein suggests acute thrombosis may have contributed to a sudden increase in intrasplenic pressure, causing a rupture in a weak spleen 1 …”

Section: Discussionmentioning

confidence: 99%

“…Spontaneous splenic rupture is a far more uncommon entity than traumatic spleen injury. Infectious diseases, hematologic disorders, and sarcoidosis are the possible causes of splenic rupture 1 . Furthermore, metastasis to the spleen from distant organs is not very frequent 2 .…”

Section: Introductionmentioning

confidence: 99%

“…Infectious diseases, hematologic disorders, and sarcoidosis are the possible causes of splenic rupture. 1 Furthermore, metastasis to the spleen from distant organs is not very frequent. 2 Meanwhile, patients with cancer are generally at high risk for thrombosis because of a predisposition to hypercoagulability.…”

Section: Introductionmentioning

confidence: 99%

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Spontaneous splenic rupture due to occult signet‐ring cell gastric cancer accompanied by a bulky splenic vein thrombosis and postoperative brain infarction: A case report

Asada,

Mori,

Takemoto

et al. 2023

Acute Medicine & Surgery

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BackgroundSplenic rupture because of metastasis from a distant organ is extremely rare.Case PresentationAn 80‐year‐old man presented with left flank pain. A computed tomography (CT) demonstrated a poorly enhanced enlarged spleen with bulky thrombus in the splenic vein without extravasations. A CT on the following day showed increased intraperitoneal hemorrhage; therefore, an emergency laparotomy was performed. The spleen was enlarged and ruptured with lacerations on its surface. Macroscopic examination showed congestion with a thrombus in the splenic vein around the hilum. Pathology revealed signet‐ring cell carcinoma. On the third postoperative day, a massive cerebral infarction in the left middle cerebral artery was revealed. Endoscopic examination demonstrated normal gastric mucosa except for some erosions, for which biopsies were performed, and two of five specimens encompassed signet‐ring cell carcinoma in the lamina propria.ConclusionOccult cancer could result in a drastic manifestation of its metastasis accompanying systemic thrombotic events.

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Section: Discussionmentioning

confidence: 99%