Spontaneous rupture of the spleen in infectious mononucleosis

Spontaneous splenic rupture in infectious mononucleosis

“…An acute increase in portal venous pressure from a Valsalva‐like manoeuvre may be responsible. Alternatively, it may be due to sudden compression of the spleen from contraction of the diaphragm or abdominal wall occurring during vigorous coughing, vomiting or defaecation 7 . This may have been the mechanism of rupture in our case.…”

Spontaneous splenic rupture resulted from infectious mononucleosis

“…It is commonly believed that it is caused by an increase in intra-abdominal pressure or contraction of the diaphragm with vigorous cough, vomiting and defecation, leading to a compression of the spleen. 4 However, Patel et al argue that it is primarily the result of an expanding subcapsular haematoma which subsequently tears the capsule and leads to haemoperitoneum. 5 Traditionally, rupture of spleen is treated by splenectomy.…”

Nonoperative Management of Spontaneous Splenic Rupture in Infectious Mononucleosis: The Role for Emerging Diagnostic and Treatment Modalities

“…Rutkow et al 3 defined IM-associated spontaneous splenic rupture as splenic rupture in patients with a history of and serologically documented IM with histopathologic changes in the spleen consistent with IM and no reported trauma (minor or major) within 6 weeks before the onset of the acute viral syndrome. The proposed mechanism of spontaneous splenic rupture has been attributed to an acute increase in portosplenovenous pressure secondary to Valsalva maneuver in an already compromised spleen 17 or to sudden compression of an enlarged spleen from diaphragmatic or abdominal wall contraction. Splenomegaly is present in virtually all patients with spontaneous rupture.…”