Spontaneous rupture of solid pseudopapillary tumor of pancreas

Abstract

Introduction: Solid pseudopapillary tumors (SPT) account for 1% to 3% of all pancreatic tumors. They have low malignant potential with a favorable prognosis, and predominantly occur in young women. The pathogenesis and clinical behavior of SPT are still uncertain. In addition, most ruptures of SPT were associated with blunt abdominal trauma, while spontaneous ruptures seemed to be quite rare. Up to now, there have been only 3 spontaneous ruptured SPT cases reported worldwide. Patient concerns: Here, we reported a 22-year-old female patient with left lower abdominal pain. Computed tomography (CT) showed that a hemorrhagic complex solid cystic mass located in the lesser omentum sac. Diagnosis: According to pathological findings of tumor specimen, the diagnosis of solid pseudopapillary tumor (SPT) of the pancreas was made. Interventions: Distal pancreatectomy and splenectomy was carried out. Outcomes: The patient recovered to normal status within 10 days after surgery. Conclusion: Besides, we reviewed about 50 cases in literatures to find out the clinical characteristics and differential diagnostic strategies of SPT.

Multicenter Study on the Diagnostic of Imaging Tests and EUS-guided fine needle aspiration of Solid Pseudopapillary Neoplasms of the Pancreas

“…In the literature, rupture of the SPN is associated with abdominal trauma or may be spontaneous, which is rare. To date, there have been only 3 cases of SPN with spontaneous rupture reported worldwide [23]. In our series, we had two young patients with blunt abdominal trauma who underwent imaging exams that suspected hematoma (1) and pseudocyst (1).…”

Urgent distal pancreatectomy for intraperitoneal hemorrhage due to the spontaneous rupture of a pancreatic metastatic tumor from synovial sarcoma: a case report

“…Spontaneous rupture of pancreatic tumors is an unusual course. There are some reports of spontaneous rupture of primary pancreatic tumors, such as cystic pancreatic tumors, SPN, and intraductal papillary mucinous neoplasms [1][2][3][4][5][6]. Some pregnancy-related cystic pancreatic tumors have the potential to grow and rupture during pregnancy [1,11].…”

“…The spontaneous rupture of a pancreatic tumor is an uncommon occurrence, although ruptured cystic pancreatic tumors, solid pseudopapillary neoplasms (SPN), and intraductal papillary mucinous neoplasms have been reported [1][2][3][4][5][6]. Metastatic tumors to the pancreas account for approximately 2% of all pancreatic tumors [7], and spontaneous rupture of metastatic pancreatic tumors is extremely rare [8].…”

Huge solid pseudopapillary tumor of the pancreas ‘Frantz tumor’: a case report

“…One of the rare presentations of SPNs is tumor rupture that is commonly seen after blunt abdominal trauma, which has been reported to represent 8% of the cases (17,22). Interestingly, Xu et al reported a spontaneous rupture of SPN in a 22 years old female who presented to the Emergency Department (ED) complaining of abdominal pain associated with leukocytosis and hemoglobin drop secondary to spontaneous SPN rupture and bleeding (22).…”

“…One of the rare presentations of SPNs is tumor rupture that is commonly seen after blunt abdominal trauma, which has been reported to represent 8% of the cases (17,22). Interestingly, Xu et al reported a spontaneous rupture of SPN in a 22 years old female who presented to the Emergency Department (ED) complaining of abdominal pain associated with leukocytosis and hemoglobin drop secondary to spontaneous SPN rupture and bleeding (22). The suggested theory of spontaneous rupture is that the cystic part of the SPN undergoes internal degeneration with a subsequent hemorrhage; consequently, if the bleeding was significant enough, it can lead to increased intramural pressure causing the spontaneous rupture (17,22).…”