Spontaneous Rupture of Pancreatic Mucinous Cystadenocarcinoma: A Case Report and Review of Literature

Woo, Yeongmin; Kim, Young Don; Jeong, Woo Jin; Jang, Hyeok Jai; Kang, Kil Hyun; Cheon, Gab Jin

doi:10.15279/kpba.2016.21.1.24

Cited by 2 publications

(2 citation statements)

References 12 publications

(7 reference statements)

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“…[ 49 – 63 ] Of these, 6 cases (40%) had an associated invasive carcinoma. [ 49 , 52 , 57 , 58 , 60 , 61 ] Even though there are not published reports of ruptured MCNs showing the relationship with malignant transformation, based on the above findings, we could hypothesize that the spontaneous rupture of an MCN expresses a malignant behavior.…”

Section: Discussionmentioning

confidence: 93%

Mucinous cystic neoplasms of the pancreas associated with pregnancy

Rego¹,

Vinatea²,

Reaño³

et al. 2020

Medicine

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Rationale: Although rare, pancreatic neoplasms can occur during pregnancy, both in benign and malignant forms. Mucinous cystic neoplasms (MCNs) of the pancreas, a type of these neoplasms, are precursor lesions to invasive pancreatic cancer. The presence of the ovarian-type stroma is a defining feature. Patient concerns: The first case was a 38-year-old woman in her 18th week of pregnancy with abdominal pain that worsens a few weeks later. The second case was a 30-year-old woman in her 17th week of pregnancy with abdominal pain in the left hypochondrium. Diagnosis: The patients were under clinical examination and laboratory test including carbohydrate antigen 19-9 (CA 19-9) and carcinoembryonic antigen (CEA). Both patients had magnetic resonance imaging (MRI). The diagnosis of a MCNs of the pancreas was done preoperatively in the 2 cases. Interventions: Both patients underwent distal pancreatectomy during pregnancy. One of them was an emergency laparotomy because of a ruptured MCN. Outcomes: Both patients were completely recovered from distal pancreatectomy and continued to full term, delivering a healthy baby by Caesarean section. After 6 years of follow-up, the first patient underwent a total gastrectomy, because of a gastric cancer with carcinomatosis. Currently the 2 patients are still alive after 8 years and 5 years of follow-up, respectively. Lessons: Surgical resection of MCNs during pregnancy should be considered during the second trimester given common distal pancreas location, rapid growth, risk of spontaneous rupture, and malignant potential.

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Section: Discussionmentioning

confidence: 93%

Mucinous cystic neoplasms of the pancreas associated with pregnancy

Rego¹,

Vinatea²,

Reaño³

et al. 2020

Medicine

View full text Add to dashboard Cite

show abstract

“… 8 Excision of the tumor with curative intent has been the principle line of management. In a case of bleeding ruptured MCN, only splenic artery ligation was done by Woo et al 9 in view of biopsy-proven peritoneal disease.…”

Section: Discussionmentioning

confidence: 99%