“…Whereas most of the women with ruptures had at least 1 risk factor, 25% of the women (21/84) did not have any 28,29,37–55 . A single risk factor was found in 47.6% (40/84) of the women 4,9,11,13,21,25,26,32,35,36,56–83 …”
Section: Resultsmentioning
confidence: 99%
“…Nine women (10.7%) had a morbidly adherent placenta, mainly a placenta percreta, 13,15,74–77,93,94,97 and 2 (2.4%) had adenomyosis 96,98 . A uterine anomaly was present in 8 ruptures (9.5%): 3 bicornuate uteri, 9,72,73 2 didelphys, 70,97 1 arcuate with right tubal occlusion, 26 and 2 unicornuate with noncommunicating rudimentary horns 32,71 …”
Section: Resultsmentioning
confidence: 99%
“…91,[94][95][96] Labor-related complications contributed to 4 ruptures; in 3 women (3.6%), 36,84,88 the labor was prolonged, and in the fourth, the labor was obstructed. 30 Nine women (10.7%) had a morbidly adherent placenta, mainly a placenta percreta, 13,15,[74][75][76][77]93,94,97 and 2 (2.4%) had adenomyosis. 96,98 A uterine anomaly was present in 8 ruptures (9.5%): 3 bicornuate uteri, 9,72,73 2 didelphys, 70,97 1 arcuate with right tubal occlusion, 26 and 2 unicornuate with noncommunicating rudimentary horns.…”
Section: Etiological and Risk Factorsmentioning
confidence: 99%
“…Four women (4.8%) died. 46,75,82,87 Thirty-nine women (48.1%) delivered a live-born fetus. Perinatal mortality was reported in 41 (50.6%).…”
Importance
Uterine rupture is defined as a nonsurgical disruption of all layers of the uterus. Most ruptures occur in the presence of a scar, usually secondary to a previous cesarean delivery. Rupture of an unscarred uterus is rare and is associated with severe maternal and neonatal outcomes.
Objective
To outline the literature on potential predisposing factors, clinical findings, and maternal and fetal outcomes of a rupture of an unscarred uterus.
Evidence Acquisition
PubMed was searched for the phrases “uterine rupture,” “unscarred,” and “spontaneous.” Individual case reports, retrospective case series, and review articles in English between 1983 and 2020 were included.
Results
We found 84 case reports in 79 articles. The mean maternal age was 29.3 (SD, 5.7) years; 38 women (45.2%) were nulliparous. Uterine rupture occurred in 37% of the women at term; in 9.9%, the gestational age was ≤12 weeks. The most common clinical presentations were abdominal pain (77.4%), signs of hypovolemic shock (36.9%), fetal distress (31%), and vaginal bleeding (22.6%). The most common risk factors were the use of uterotonic drugs for induction or augmentation of labor and a prior curettage procedure. The most frequently ruptured site was the body of the uterus. Hysterectomy managed 36.9% of the ruptures. Four women died (4.8%). Perinatal mortality was 50.6%. Perinatal death was higher in developing than developed countries.
Conclusions and relevance
Although rare, spontaneous rupture of the unscarred uterus has serious consequences to the mother and the fetus and should be included in the differential diagnosis of acute abdomen in pregnancy.
Target Audience
Obstetrician-gynecologists, family medicine physicians.
Learning Objectives
After completing this activity, the learner will be better able to describe the consequences of spontaneous rupture of the unscarred uterus to the mother and fetus; discuss risk factors for spontaneous rupture of the unscarred uterus and its potential occurrence in nulliparous, antepartum, and the first trimester; and discuss how timely assessment of a pregnant woman presenting with abdominal pain impacts survival of the mother and child.
“…Whereas most of the women with ruptures had at least 1 risk factor, 25% of the women (21/84) did not have any 28,29,37–55 . A single risk factor was found in 47.6% (40/84) of the women 4,9,11,13,21,25,26,32,35,36,56–83 …”
Section: Resultsmentioning
confidence: 99%
“…Nine women (10.7%) had a morbidly adherent placenta, mainly a placenta percreta, 13,15,74–77,93,94,97 and 2 (2.4%) had adenomyosis 96,98 . A uterine anomaly was present in 8 ruptures (9.5%): 3 bicornuate uteri, 9,72,73 2 didelphys, 70,97 1 arcuate with right tubal occlusion, 26 and 2 unicornuate with noncommunicating rudimentary horns 32,71 …”
Section: Resultsmentioning
confidence: 99%
“…91,[94][95][96] Labor-related complications contributed to 4 ruptures; in 3 women (3.6%), 36,84,88 the labor was prolonged, and in the fourth, the labor was obstructed. 30 Nine women (10.7%) had a morbidly adherent placenta, mainly a placenta percreta, 13,15,[74][75][76][77]93,94,97 and 2 (2.4%) had adenomyosis. 96,98 A uterine anomaly was present in 8 ruptures (9.5%): 3 bicornuate uteri, 9,72,73 2 didelphys, 70,97 1 arcuate with right tubal occlusion, 26 and 2 unicornuate with noncommunicating rudimentary horns.…”
Section: Etiological and Risk Factorsmentioning
confidence: 99%
“…Four women (4.8%) died. 46,75,82,87 Thirty-nine women (48.1%) delivered a live-born fetus. Perinatal mortality was reported in 41 (50.6%).…”
Importance
Uterine rupture is defined as a nonsurgical disruption of all layers of the uterus. Most ruptures occur in the presence of a scar, usually secondary to a previous cesarean delivery. Rupture of an unscarred uterus is rare and is associated with severe maternal and neonatal outcomes.
Objective
To outline the literature on potential predisposing factors, clinical findings, and maternal and fetal outcomes of a rupture of an unscarred uterus.
Evidence Acquisition
PubMed was searched for the phrases “uterine rupture,” “unscarred,” and “spontaneous.” Individual case reports, retrospective case series, and review articles in English between 1983 and 2020 were included.
Results
We found 84 case reports in 79 articles. The mean maternal age was 29.3 (SD, 5.7) years; 38 women (45.2%) were nulliparous. Uterine rupture occurred in 37% of the women at term; in 9.9%, the gestational age was ≤12 weeks. The most common clinical presentations were abdominal pain (77.4%), signs of hypovolemic shock (36.9%), fetal distress (31%), and vaginal bleeding (22.6%). The most common risk factors were the use of uterotonic drugs for induction or augmentation of labor and a prior curettage procedure. The most frequently ruptured site was the body of the uterus. Hysterectomy managed 36.9% of the ruptures. Four women died (4.8%). Perinatal mortality was 50.6%. Perinatal death was higher in developing than developed countries.
Conclusions and relevance
Although rare, spontaneous rupture of the unscarred uterus has serious consequences to the mother and the fetus and should be included in the differential diagnosis of acute abdomen in pregnancy.
Target Audience
Obstetrician-gynecologists, family medicine physicians.
Learning Objectives
After completing this activity, the learner will be better able to describe the consequences of spontaneous rupture of the unscarred uterus to the mother and fetus; discuss risk factors for spontaneous rupture of the unscarred uterus and its potential occurrence in nulliparous, antepartum, and the first trimester; and discuss how timely assessment of a pregnant woman presenting with abdominal pain impacts survival of the mother and child.
“… Report author/year Risk factors gravity, parity GA/peripartum period Type of PASD Outcomes Esmans et al, (2004) [14] Manual removal of placenta and curettage 14 weeks Percreta Spontaneous uterine rupture Hypovolemic Blood loss up to 3000 ml Required 4 unit of blood transfusion. Hysterectomy Huang et al, (2005) [15] G3P2, near cornual pregnancy 16 weeks Accreta In fatal condition due to massive hemorrhage. Multiple organ failure Emergency hysterectomy Enebe et al, (2019) [15] multiparous 33 weeks Percreta Spontaneous uterine rupture Hypovolemic shock Intrauterine foetal death Okaniwa et al, (2020) [5] Use of uterotonics and manual removal of placenta 39 weeks, second day of postpartum Accreta Hysterectomy.…”
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