Spontaneous Rupture of a Splenic Artery Aneurysm in Pregnancy: Report of Two Cases

Natural history and management of splanchnic artery aneurysms in a single tertiary referral center

“…[13][14][15] We report in our cohort that the desire to pursue fertility treatment in the presence of an SAA was an indication to undergo repair of one aneurysm, which is certainly in agreement with the reported literature. [16][17][18][19][20] Aneurysm location. One important aspect that we encountered in our cohort was the relatively large number of celiac artery aneurysms (46% instead of <5%) and the relatively low number of splenic artery aneurysms (30% instead of >60%) that are mostly reported in the literature.…”

A rare case of gastric varices and splenic artery aneurysm secondary to splenic arteriovenous fistula

“…Prevalence of SAA was 0.1% to 0.2% in an autopsy study ( 14 ), while a study of 3,600 arteriograms found an incidence of 0.78% ( 15 ). Rupture of SAA is associated with a 25% mortality, and management of these entities should be done in consultation with general surgery and interventional radiology ( 16 ). Different approaches include resection with or without splenectomy, surgical ligation, and endovascular techniques, including transcatheter arterial embolization and covered stent exclusion.…”

Rupture of a splenic artery aneurysm during pregnancy with maternal and foetal death

“…Postulated pathogenetic mechanisms for the association of SAA with pregnancy include hormonal and mechanical factors. Oestrogen and progesterone have been demonstrated to have receptors in arterial walls and presumably exert some structural influence on the integrity of blood vessels (Selo-Ojeme and Welch, 2003), whilst relaxin, a hormone secreted in late pregnancy, has been implicated in the creation of the fibrodysplastic lesions with fragmentation of elastica seen in blood vessels in pregnancy (Shahabi et al, 2000).…”

“…An association between this entity during pregnancy and the recognition of a ruptured SAA as a rare cause of maternal death is well-documented with Corson first describing in 1869 the sudden and unexpected death of a 29-year-old multigravida at eight months gestation in whom the diagnosis was only made following post-mortem examination (Corson, 1869). The condition is associated with significant maternal and foetal mortality with rates as high as 75% and 95% respectively (Shahabi et al, 2000). We report a case of sudden unexpected maternal and foetal death at eight months gestation where the diagnosis was not suspected clinically and only made at autopsy following meticulous dissection.…”