Spontaneous Resolution of Chronic Hepatitis C – A Case Report

Abstract

We experienced a case of chronic hepatitis C showing spontaneous resolution. The patient was diagnosed as having chronic hepatitis with moderate activity, non‐A non‐B type, after laparoscopy with liver histology in 1982, and was followed up thereafter at our out‐patient clinic. His aspartate aminotransferase (AST)and alanine aminotransferase (ALT) levels fluctuated but had stabilized by 1990. A second laparoscopy with liver histology, conducted in 1993, revealed non‐specific reactive hepatitis. Serum hepatitis C virus RNA (HCV‐RNA) had been strongly positive in 1982 but was negative in 1990. Interferon therapy may not be indicated in such cases.