Spontaneous Resolution of a Caseous Calcification of the Mitral Annulus

Correale, Michele; Deluca, Giovanni; Ieva, Riccardo

doi:10.1590/s1807-59322009001100015

Cited by 20 publications

(22 citation statements)

References 11 publications

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“…Slicing the 3DTEE datasets and viewing them en face showed the mass to consist of highly echogenic band‐like and punctate areas consistent with discrete areas of calcification embedded in a less echogenic matrix. This appearance correlated with the pathological findings of calcific granules/strands located in a liquefied or semiliquefied interior presenting a typical tooth‐paste like appearance 10,17 . The highly echogenic outer border represented the residual outer portion or rim of the calcific mass which did not undergo liquefaction.…”

supporting

confidence: 70%

Live/Real Time Three‐Dimensional Transesophageal Echocardiographic Findings in Caseous Mitral Annular Calcification

Assudani

Singh²,

Samar³

et al. 2010

Echocardiography

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We describe a 77-year-old female with hypertrophic cardiomyopathy in whom live/real time three-dimensional transesophageal echocardiography (3DTEE) provided incremental value over two-dimensional transthoracic and transesophageal echocardiography (2DTTE, 2DTEE) and three-dimensional transthoracic echocardiography (3DTTE) in making a more comprehensive assessment and a more confident diagnosis of caseous mitral annular calcification. 3DTEE revealed a portion of the mass to consist of small, multiple, highly echogenic discrete band-like and punctate areas within a relatively much less echogenic stroma and surrounded by a well defined highly echogenic border. This appearance correlated with the pathological findings of calcific granules/strands located in a liquefied or semiliquefied interior providing a typical toothpaste like appearance. The highly echogenic outer border represented the residual outer portion or rim of the calcific mass which did not undergo liquefaction. These findings on 3DTEE which correlated with the toothpaste like appearance seen at surgery were not visualized on 2DTTE, 2DTEE, and 3DTTE.

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supporting

confidence: 70%

Live/Real Time Three‐Dimensional Transesophageal Echocardiographic Findings in Caseous Mitral Annular Calcification

Assudani

Singh²,

Samar³

et al. 2010

Echocardiography

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“…CCMA tends to occur in older patients (mean age 69 years) and is associated with hypertension . CCMA typically involves the posterior mitral annulus, and it rarely involves only the anterior annulus or both annuli …”

Section: Prevalencementioning

confidence: 99%

“…As the prevalence of CCMA is higher in patients with end‐stage renal disease, especially those on dialysis, an altered calcium phosphate metabolism is implicated in its pathogenesis . It is thought that lipid‐laden macrophages may be implicated in the liquefaction necrosis and development of CCMA, because high serum cholesterol is associated with MAC …”

Section: Pathology and Pathophysiologymentioning

confidence: 99%

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Caseous Calcification of the Mitral Annulus: A Review

Elgendy

Conti

2013

Clinical Cardiology

132

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Caseous calcification of the mitral annulus (CCMA) is a rare variant of mitral annular calcification (MAC). Since most cardiologists are unfamiliar with CCMA, it is commonly misdiagnosed as an abscess, tumor or infective vegetation on the mitral valve. In most cases, conservative management for this lesion is sufficient. In this review, we will discuss the various aspects of this condition and illustrate the gross and histologic pathology as well as various imaging modalities (Ultrasound, Computed tomography, Cardiac Magnetic resonance) to assess this unusual cardiac mass.

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“…Because it appears similar to various diseases such as a tumor, abscess, or thrombus, misdiagnoses and unnecessary surgical resections have been reported . Cases of retransformation of CCMA into MAC and spontaneous resolution have also been reported. Although CCMA is usually a benign, asymptomatic condition, it can cause hemodynamic or embolic complications .…”

Section: Discussionmentioning

confidence: 99%