“…The frequency of SR varies based on the type of cancer, occurring at a rate of about 1 out of every 60,000 to 100,000 cases of all cancers [ 2 , 4 , 5 , 6 , 7 , 8 , 9 , 10 , 11 , 12 ]. The mechanisms of SR are not fully understood, but several putative mechanisms have been proposed, including inflammation, apoptosis, ischemia, and immunological responses [ 2 , 4 , 5 , 6 , 7 , 8 , 9 , 10 , 11 , 12 , 13 ]. Moreover, additional mechanisms suggested to explain the phenomenon of SR include epigenetic modifications, hormonal responses, oncogenes, tumor suppressors, cytokines, growth factors, and psychological factors [ 2 , 4 , 5 , 6 , 7 , 8 , 9 , 10 , 11 , 12 , 13 ].…”