Spontaneous Progression of a Long-Standing Lamellar Macular Hole into a Full-Thickness Macular Hole

Castro, L. C.; Duker, Jay S.

doi:10.3928/15428877-20100215-54

Cited by 5 publications

(5 citation statements)

References 9 publications

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“…Sixteen studies 2,3,5,6 –18 with a combined sample of 76 eyes (n = 76) were included (Table 1). Thirteen studies 2,3,6 –12,14 –17 (n = 40) used ILM peeling, 1 study 5 (n = 32) used inverted ILM flap techniques, and 2 studies 13,18 (n = 4) did not specify the surgical technique.…”

Section: Resultsmentioning

confidence: 99%

Surgical Management of Full-Thickness Macular Holes Spontaneously Arising From Lamellar Macular Holes

Garg,

Wahab,

Yan

2023

Journal of VitreoRetinal Diseases

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Introduction: To review the literature regarding surgical management of full-thickness macular holes (FTMHs) spontaneously arising from lamellar MHs (LMHs). Methods: The literature on surgically managed FTMHs arising from LMHs was reviewed via Ovid MEDLINE and Embase through June 5, 2022. Results: Seventy-six eyes from 16 articles were included. Forty eyes had internal limiting membrane (ILM) peeling, 32 inverted ILM flap techniques, and 4 an unclear surgical technique. The FTMH closure rate was not significantly different between ILM peeling (34/40 [85%]) and the inverted ILM flap techniques (28/32 [88%]) ( P = .761). The mean (±SD) logMAR visual acuity improved from 0.64 ± 0.46 to 0.25 ± 0.22 (Snellen 20/87 to 20/36) with ILM peeling (n = 30); similar data were not available for inverted ILM flap techniques. Conclusions: Foveal tissue loss, flat hole edges, and limited retinal hydration may result in inverted ILM flap techniques having outcomes similar to those of ILM peeling in repairing FTMHs from LMHs. Future studies are needed to compare techniques.

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Section: Resultsmentioning

confidence: 99%

Surgical Management of Full-Thickness Macular Holes Spontaneously Arising From Lamellar Macular Holes

Garg,

Wahab,

Yan

2023

Journal of VitreoRetinal Diseases

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“…17 Therefore, this possible morphology of MH formation is still reported occasionally. [18][19][20] We postulated that, in this case, the Müller cell cone might have been damaged by a defect of the inner foveal retina and the subsequent development of the ERM seemed to lead to centrifugal disruption of the remaining outer retinal layer at the fovea.…”

Section: Discussionmentioning

confidence: 95%

Macular Hole Formation After Vitreomacular Detachment With an Operculum

Takahashi

Nagaoka²,

Yoshida³

2016

RETINAL Cases &Amp; Brief Reports

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In this case, the MH resulted from the tangential traction caused by the epiretinal membrane after vitreomacular detachment developed; the MH was accompanied by a small round operculum, a retinal dimple beneath the membrane, and a tightrope-like structure that bridged the hole edges. The operculum likely comprised a detached inner foveal retina alone and did not include retinal photoreceptor cells.

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“…Casparis and Bovey8 noted that the foveal photoreceptor layer did not appear to be thinned or particularly irregular on OCT in more recent LMH, but in patients with long-term LMH, these tissues looked thin and irregular. In addition, there are case reports of patients who progressed from LMH to full-thickness macular hole 3,9. In contrast with these reports, Theodossiadis et al observed spontaneous closure of LMH in two patients 11 and 21 months after the baseline examination 10.…”

Section: Discussionmentioning

confidence: 98%

“…In recent years, there has been increasing evidence that surgery may be beneficial in certain patients with LMH, and surgery is being seen increasingly as a reasonable option compared with observation in more symptomatic patients 8,9. To the best of our knowledge, no study has compared the results of a surgical approach versus observation in these patients.…”

Section: Introductionmentioning

confidence: 99%

Surgical therapy versus observation for lamellar macular hole: a retrospective comparison study

Sanisoğlu

Elbay²,

Şahin³

et al. 2013

OPTH

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BackgroundThe purpose of this study was to compare anatomic and visual changes in patients with lamellar macular hole undergoing pars plana vitrectomy with those in patients undergoing follow-up only.MethodsIn this retrospective consecutive case series study, we evaluated two groups of eyes, comprising 19 eyes from 19 patients with lamellar macular hole who underwent pars plana vitrectomy with internal limiting membrane peeling and 21 eyes from 21 patients with lamellar macular hole who had follow-up only. Corrected distance visual acuity (CDVA, in logMAR) and optical coherence tomography findings, including measurements of maximum diameter of lamellar defect and foveal thickness, and whether the inner segment/outer segment band was intact or not were documented at initial and follow-up examinations.ResultsAt initial examination, mean CDVA was 0.54 logMAR in the study group and 0.51 logMAR in the control group, and 0.33 logMAR and 0.55 logMAR, respectively, on final examination. In the study group, postoperative optical coherence tomography images were found to be normalized in ten patients (52.6%), improved in six (31.5%), unchanged in two (10.5%), and to have progressed to full-thickness macular hole in one (5.2%) in the intervention group, while all patients in the control group were found to have deteriorated within the follow-up period between March 2004 and June 2010.ConclusionIn patients with lamellar macular hole, combination treatment with pars plana vitrectomy and internal limiting membrane peeling appears to be effective, but further studies are required to establish new treatment modalities for patients who do not have a satisfactory outcome from treatment.

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Spontaneous Progression of a Long-Standing Lamellar Macular Hole into a Full-Thickness Macular Hole

Cited by 5 publications

References 9 publications

Surgical Management of Full-Thickness Macular Holes Spontaneously Arising From Lamellar Macular Holes

Surgical Management of Full-Thickness Macular Holes Spontaneously Arising From Lamellar Macular Holes

Macular Hole Formation After Vitreomacular Detachment With an Operculum

Surgical therapy versus observation for lamellar macular hole: a retrospective comparison study

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