Spontaneous pregnancy and birth with corrected cloacal exstrophy

Gezer, Altay; Güralp, Onur; Yeşilbaş, Cengiz; Madazli, Rıza

doi:10.1111/j.1600-0412.2011.01076.x

Cited by 10 publications

(5 citation statements)

References 3 publications

(3 reference statements)

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“…Childbirth is sporadically reported among both PC patients [31, 32] and CE patients [33]. One PC case delivered vaginally in the first pregnancy, and then cesarean section was performed for a triplets pregnancy after in vitro fertilization [31, 32].…”

Section: Resultsmentioning

confidence: 99%

The current profile of persistent cloaca and cloacal exstrophy in Japan: the results of a nationwide survey in 2014 and a review of the literature

Kubota

2017

Pediatr Surg Int

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PurposeThe current profile of persistent cloaca (PC) and cloacal exstrophy (CE) in Japan was first examined in 2014.Materials and methodsInformation was obtained by sending a questionnaire to 244 university hospitals and children’s hospitals.ResultsResponses from 113 institutions reported 466 PC cases and 229 CE cases. The incidences of PC and CE from 1980 to 2012 were 0.97 and 0.49 per 100,000 live births, respectively. In the previous 5 years, antenatal abnormalities were found in 57.6% of PC and 72.7% of CE patients. Myelomeningocele was observed in 45.6% of CE patients. As a result of various surgical treatments used in the neonatal and infantile periods, the respective rates of bladder dysfunction, clean intermittent catheterization, and permanent enterostomy were 32.6, 22.5, and 7.3% in PC patients and 60.7, 28.4, and 73.8% in CE patients. Menstrual outflow obstruction was found in 22.5% of PC and 48.9% of CE patients with menstruation.ConclusionThe clinical outcomes of PC and CE remain unsatisfactory. Therefore, the establishment of treatment guidelines might be a useful objective for improving the current status of PC and CE.

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Section: Resultsmentioning

confidence: 99%

The current profile of persistent cloaca and cloacal exstrophy in Japan: the results of a nationwide survey in 2014 and a review of the literature

Kubota

2017

Pediatr Surg Int

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“…In patients with continent anal urinary diversion, a pregnancy rate of 31% has been reported in one retrospective study, where 5 (of 14) women became pregnant and delivered 6 healthy children [ 6 ]. At least one case report describes a pregnancy in a woman after cloacal extrophy repair [ 15 ].…”

Section: Discussionmentioning

confidence: 99%

Course of an unplanned and unexpected pregnancy in a 39 year-old patient with Complex bladder extrophy: a case report

Schrey-Petersen,

Lacher,

Stepan

2023

J Med Case Reports

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Background With improved operative techniques pregnancy rates have been rising in patients with anomalies of the extrophy-epispadias-complex, including also female patients with bladder extrophy. Specific risks around pregnancy need to be addressed sufficiently beforehand. Case presentation An unplanned pregnancy was detected at 34 weeks in a 39-year old White female patient with former complex bladder extrophy. Decades after her operation she had not received any follow-up medical care and believed to be unable to conceive due to her anomaly. Thus no contraceptive matters were taken. The patient had lived in a stable relationship with regular sexual intercourse for many years. Until 34 weeks the pregnancy was uncomplicated, but then uterine prolapse and signs of beginning pre-eclampsia appeared, and a healthy girl was born with cesarean section. Conclusion As patients with bladder extrophy and other anomalies from the extrophy-epispadias-complex reach adolescence/adulthood, they need continuous medical follow-up and transition of care to adult surgery and gynecology in order to address specific aspects of sexual health, reproduction, contraception, and also cancer screening. In the presented case lack of transition of care resulted in an unplanned and complicated pregnancy.

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“…In general, females born with OEIS can expect to face considerable challenges in life, not only relating to extensive operations and highrisk pregnancies, but also to urinary incontinence, poor body image, uterine prolapse, and fertility issues [6,13,15]. Documenting the rare success story of an OEIS pregnancy is vital for learning more about how to care for future similar cases.…”

Section: Discussionmentioning

confidence: 99%

“…At 35 weeks, the patient developed preeclampsia with proteinuria, necessitating delivery via primary cesarean section with ovarian cystectomy and/or possible salpingo-oophorectomy. Given her extensive adhesions from past corrective procedures and because of the large ovarian cyst requiring excision, cesarean section was performed via a midline vertical abdominal incision with a classical uterine incision [1,6].…”

Section: Case Reportmentioning

confidence: 99%

A case of congenital cloacal exstrophy/omphalocele-exstrophy-imperforate anus-spinal defects syndrome and a successful pregnancy

Seat

Boxwalla

Hough

et al. 2022

Clin Exp Reprod Med

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Herein, we report an exceptionally rare case of a 25-year-old woman with cloacal exstrophy/omphalocele-exstrophy-imperforate anus-spinal defects (OEIS) syndrome achieving a viable pregnancy despite many gastrointestinal and genitourinary malformations and multiple respective corrective operations. The patient was born with two vaginas, two uteruses, four ovaries, an imperforate anus, a large omphalocele including bowel and bladder exstrophy, and diaphysis of the pubic rami. This patient is the only documented OEIS patient not to have tethered spinal cord as an anomaly, perhaps contributing to her successful pregnancy. After experiencing preeclampsia with severe features at 35 weeks, the baby was born via cesarean section.

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Spontaneous pregnancy and birth with corrected cloacal exstrophy

Cited by 10 publications

References 3 publications

The current profile of persistent cloaca and cloacal exstrophy in Japan: the results of a nationwide survey in 2014 and a review of the literature

The current profile of persistent cloaca and cloacal exstrophy in Japan: the results of a nationwide survey in 2014 and a review of the literature

Course of an unplanned and unexpected pregnancy in a 39 year-old patient with Complex bladder extrophy: a case report

A case of congenital cloacal exstrophy/omphalocele-exstrophy-imperforate anus-spinal defects syndrome and a successful pregnancy

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