Spontaneous pneumothorax in Covid-19: Report of three cases

Montoya, Daniel Alfredo Pacheco; Ortega-Rosales, Alberto; Malla-Gonzalez, Alexis; Jimenez-Sarango, Augusto

doi:10.1016/j.radcr.2021.12.047

Cited by 2 publications

(2 citation statements)

References 13 publications

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“…6 Recent case reports have mentioned delayed PTX after many weeks of COVID-19 infection. 28,29 This adds more complexity to the pathophysiological basis of the disease as one would expect the lung parenchymal inflammation in these patients to have mostly resolved by this time point. There are certainly other unknown factors contributing to PTX development and further research is required.…”

Section: Pathophysiologymentioning

confidence: 99%

COVID-19-Related Pleural Diseases

Iqbal

Rahman

Hallifax

2023

Semin Respir Crit Care Med

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Coronavirus disease 2019 (COVID-19)-related pleural diseases are now well recognized. Since the beginning of the pandemic, increasing cases of pleural diseases including pneumothorax, pneumomediastinum, and pleural effusion with severe COVID-19 infection have attracted the attention of physicians and are not incidental or due to barotrauma. The complicated course of COVID-19 illness highlights the complex pathophysiological underpinnings of pleural complications. The management of patients with pneumothorax and pneumomediastinum is challenging as the majority require assisted ventilation; physicians therefore appear to have a low threshold to intervene. Conversely, pleural effusion cases, although sharing some similar patient characteristics with pneumothorax and pneumomediastinum, are in general managed more conservatively. The evidence suggests that patients with COVID-19-related pleural diseases, either due to air leak or effusion, have more severe disease with a worse prognosis. This implies that prompt recognition of these complications and targeted management are key to improve outcomes.

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Section: Pathophysiologymentioning

confidence: 99%

COVID-19-Related Pleural Diseases

Iqbal

Rahman

Hallifax

2023

Semin Respir Crit Care Med

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“…5 It was reported as a rare complication in COVID-19 patients occurs only in 1% or less of patients. 6,7 The prompt identification and management of pneumothorax in such patients are essential as it worsens the hypoxia and hence requires immediate intervention. Spontaneous pneumothorax caused by COVID-19 has been recorded on several occasions at the time of diagnosis or during therapy.…”

Section: Introductionmentioning

confidence: 99%

Pneumothorax in Critically Ill COVID-19 Patients: Prevalence, Analysis of Risk Factors and Clinical Outcomes

AlGhamdi¹,

AlQahtani²,

AlDajani³

et al. 2022

IJGM

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Background: Previous studies have been conducted to assess pneumothorax. However, few studies were done to assess pneumothorax in COVID-19 patients in the intensive care unit (ICU). Objective: Our aim is to describe and analyze the prevalence, clinical characteristics, risk factors, and outcomes of COVID-19 pneumothorax patients in the intensive care unit. Methods: We performed a retrospective review of the medical records of 418 patients, who tested positive for COVID-19 by polymerase chain reaction test and required ICU admission in King Fahad Hospital of The University from 02/01/2020 to 01/09/2021. A total number of 36 pneumothorax patients were included in the study. Results: Of 418 patients who were followed up in the intensive care unit as COVID-19 cases, 36 patients developed a pneumothorax (8.61%). The mean age of the patients was 55.6 ± 15.06 years, 23 patients were male, and 13 were female. Seventeen patients were obese, and only one patient was an active smoker. Twenty-four patients had at least one comorbidity; hypertension was the most common. Thirty-two patients were intubated, and the duration of intubation was 23.23 ±15.9 days. The time from intubation to pneumothorax development was 8.8 ± 9.3 days. Six patients were on bilevel positive airway pressure ventilation (BIPAP), 2 patients on continuous positive airway pressure ventilation (CPAP), 3 patients on High-Flow Nasal Cannula ventilation (HFNC), 9 patients on pressure-control ventilation (PC), and 16 patients on pressure regulated volume control ventilation (PRVC). Of 36 patients, 26 died, and the mortality rate was 72.2%. Conclusion: Our study showed that risk factors of pneumothorax occurrence in COVID-19 critically ill patients include male patients, hypertension, diabetes mellitus, endotracheal intubation and mechanical ventilation. More efforts should be made to determine the risk factors and assess the outcomes of those patients to develop preventive measures and management guidelines.

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Spontaneous pneumothorax in Covid-19: Report of three cases

Cited by 2 publications

References 13 publications

COVID-19-Related Pleural Diseases

COVID-19-Related Pleural Diseases

Pneumothorax in Critically Ill COVID-19 Patients: Prevalence, Analysis of Risk Factors and Clinical Outcomes

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