Spontaneous Pneumomediastinum: Rare Complication of Tracheomalacia

Lal, Amos; Mishra, Ajay Kumar; Sahu, Kamal Kant; Noreldin, Mohsen

doi:10.1016/j.arbres.2019.09.017

Cited by 8 publications

(2 citation statements)

References 9 publications

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“…5 There are some predisposing and precipitating factors such as asthma, respiratory infections, inhaled drug use, corticosteroids, inhalation of irritants, and other conditions as well as some anatomical predisposing alterations including tracheomalacia. [5][6][7][8] SPM is rarely reported in patients affected by COVID-19 pneumonia, and it could represent a potential radiological indicator of progression. 9 Loculated pneumothorax (LPNX) is also a rare condition and is mainly associated with acute distress respiratory syndrome (ARDS) in patients who are mechanically ventilated.…”

Section: Introductionmentioning

confidence: 99%

Unusual presentations of COVID-19 pneumonia on CT scans with spontaneous pneumomediastinum and loculated pneumothorax: A report of two cases and a review of the literature.

Brogna¹,

Bignardi

Salvatore³

et al. 2020

Heart & Lung

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Section: Introductionmentioning

confidence: 99%

Unusual presentations of COVID-19 pneumonia on CT scans with spontaneous pneumomediastinum and loculated pneumothorax: A report of two cases and a review of the literature.

Brogna¹,

Bignardi

Salvatore³

et al. 2020

Heart & Lung

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“…Spontaneous pneumomediastinum is a rare clinical disease defined as the presence of free air in mediastinal structures without apparent cause such as trauma [11]. This clinical condition may be due to leakage of air from ruptured wall of marginal pulmonal alveoli, secondary to the high intra-alveolar pressure caused by factors such as artificial ventilation or a severe cough.…”

Section: Introductionmentioning

confidence: 99%

Delayed Pneumomediastinum and Subcutaneous Emphysema in Covid-19 Patients: A Case Report

Moradi

Dr.yekefallah

Sedighi

et al. 2020

J Qazvin Univ Med Sci

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Coronavirus Disease 2019 (COVID-19) is a severe respiratory disease initiated on December 2019. Genome sequence analysis shows that the pathogen is a complex beta-coronavirus RNA, known as Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2). Spontaneous Pneumomediastinum and pneumothorax are rare clinical and radiological conditions associated with COVID-19. This study is case report of pneumomediastinum and subcutaneous emphysema in two patients with COVID-19, while investigating the clinical and paraclinical symptoms and the treatment process of two cases. Finding factors related to the severity of COVID-19 for improving the final outcome in patients is very important.

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Spontaneous subcutaneous emphysema and pneumomediastinum in non-intubated patients with COVID-19

et al. 2020

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Purpose We describe the presenting characteristics and hospital course of 11 novel coronavirus (COVID-19) patients who developed spontaneous subcutaneous emphysema (SE) with or without pneumomediastinum (SPM) in the absence of prior mechanical ventilation. Materials and methods A total of 11 non-intubated COVID-19 patients (8 male and 3 female, median age 61 years) developed SE and SPM between March 15 and April 30, 2020 at a multi-center urban health system in New York City. Demographics (age, gender, smoking status, comorbid conditions, and body-mass index), clinical variables (temperature, oxygen saturation, and symptoms), and laboratory values (white blood cell count, C-reactive protein, D-dimer, and peak interleukin-6) were collected. Chest radiography (CXR) and computed tomography (CT) were analyzed for SE, SPM, and pneumothorax by a board-certified cardiothoracic-fellowship trained radiologist. Results Eleven non-intubated patients developed SE, 36% (4/11) of whom had SE on their initial CXR. Concomitant SPM was apparent in 91% (10/11) of patients, and 45% (5/11) also developed pneumothorax. Patients developed SE on average 13.3 days (SD: 6.3) following symptom onset. No patients reported a history of smoking. The most common comorbidities included hypertension (6/11), diabetes mellitus (5/11), asthma (3/11), dyslipidemia (3/11), and renal disease (2/11). Four (36%) patients expired during hospitalization. Conclusion SE and SPM were observed in a cohort of 11 non-intubated COVID-19 patients without any known cause or history of invasive ventilation. Further investigation is required to elucidate the underlying mechanism in this patient population.

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Spontaneous Pneumomediastinum: Rare Complication of Tracheomalacia

Cited by 8 publications

References 9 publications

Unusual presentations of COVID-19 pneumonia on CT scans with spontaneous pneumomediastinum and loculated pneumothorax: A report of two cases and a review of the literature.

Unusual presentations of COVID-19 pneumonia on CT scans with spontaneous pneumomediastinum and loculated pneumothorax: A report of two cases and a review of the literature.

Delayed Pneumomediastinum and Subcutaneous Emphysema in Covid-19 Patients: A Case Report

Spontaneous subcutaneous emphysema and pneumomediastinum in non-intubated patients with COVID-19

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