Spontaneous monochorionic tetra-amniotic quadruplet pregnancy at term

Nnadi, Daniel; Ibrahim, Ango; Nwobodo, EI

doi:10.4103/2278-960x.112597

Cited by 8 publications

(20 citation statements)

References 5 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Although a dramatic rise in the incidence of multiple gestations seems to be there due to the use of ovulation induction drugs and in vitro fertilization, spontaneous quadruplet pregnancy is still very uncommon. [2][3][4]7 As per Hellin rule, the incidence is one in 512,000 to one in 677,000 births, and is associated with greater maternal and perinatal mortality and morbidity. 5,6 Nnadi et al has reported the incidence of such higher order multiple pregnancies ranging from 0.01% to 0.07% of all pregnancies.…”

Section: Case Reportmentioning

confidence: 99%

“…5,6 Nnadi et al has reported the incidence of such higher order multiple pregnancies ranging from 0.01% to 0.07% of all pregnancies. 7 Till 1999, only 128 sets of quadruplet pregnancy were recorded across the world. 8 In Nepal, only two such cases have been reported before in newspaper media, thus making it one of its first kind to be published in literature.…”

Section: Case Reportmentioning

confidence: 99%

See 1 more Smart Citation

Successful Management of Quadruplet Pregnancy following Spontaneous Conception

Shrestha¹,

Thapa²,

Aryal³

et al. 2016

J Lumbini Med Coll

View full text Add to dashboard Cite

Introduction: When more than two fetuses simultaneously develop in the uterus, it is called higher order multiple pregnancy. The incidence of such pregnancies ranges from 0.01% to 0.07%. Case report: We report a case of 26-year-old G2P1L0D2 with previous history of preterm vaginal twin delivery, diagnosed to have quadruplet pregnancy. She was admitted at 28 weeks of gestation for safe confinement. At 33 weeks of gestation, emergency cesarean section was conducted with outcome of two female and two male babies with quadriamniotic and quadrichorionic placenta, without any intra and post-operative complications. Conclusion: A multidisciplinary approach with good neonatal care facilities is warranted for a better outcome in higher order multiple pregnancies.

show abstract

Section: Case Reportmentioning

confidence: 99%

Section: Case Reportmentioning

confidence: 99%

Successful Management of Quadruplet Pregnancy following Spontaneous Conception

Shrestha¹,

Thapa²,

Aryal³

et al. 2016

J Lumbini Med Coll

View full text Add to dashboard Cite

show abstract

“…Liu in 2010 [19] reported a case of a monozygotic quadruplet pregnancy as a result of IVF, although the pregnancy ended in the ninth week of gestation due to chromosomal abnormalities. Nnadi in 2013 [20] described a case of monozygotic quadruplet pregnancy conceived naturally that ended in an elective cesarean section of a set of monochorionic tetra-amniotic quadruplets at 37 weeks of gestation. Neubecker in 1962 [21] and Rau in 1940 [22] reported two cases of monozygotic quintuplet pregnancies, indicating the possibility of a quadruplet and quintuplet pregnancy arising from a single ovum.…”

Section: Pathophysiology Of High-order Pregnancymentioning

confidence: 99%

“…Malpresentations are common, while the babies often require intensive care and special treatment, considering that more than 90% of high-order pregnancies are born prematurely. Average gestational age at delivery is estimated around 29.5 weeks for quadruplets and 29 weeks for quintuplets [17], although term delivery has also been reported, mostly as case reports [20,134,135]. The rates of preterm birth in the USA at <37 weeks of gestation are estimated at 96.77% for quadruplets and 100% for quintuplets and more.…”

Section: Delivery Of a Quadruplet Or Quintuplet Pregnancymentioning

confidence: 99%

Quadruplets and Quintuplets

Fiorentzis¹,

Salta²,

Pargianas³

et al. 2019

Multiple Pregnancy - New Challenges

View full text Add to dashboard Cite

A high-order pregnancy is always a challenge not only for the couple but also for the obstetrician, the pediatricians, the midwives, and the whole stuff of an obstetric clinic. The breakthroughs of infertility treatments have made more couples to postpone the birth of their children until they feel professionally and financially safe, many times after the age of 40. The advanced age of the mother puts extra pressure to the clinician for immediate success, leading to a rise of high-order pregnancies until the introduction of regulations and laws in many countries. The cost of a quadruplet and quintuplet pregnancy can be unbearable, not only financially but also psychologically. The management of such a pregnancy is also challenging since its beginning and to the end. Modern techniques and methods can also be difficult to be implemented on a quadruplet of quintuplet pregnancy because of the fear of losing four or five embryos at once. At the same time, the limited number of cases makes it almost impossible for studies to be made and guidelines to be established for most of the cases.

show abstract

“…Higher-order (triplet or more) multiple pregnancies occur when more than two fetuses are present in the uterus at the same time. (1) (2) High order multiple pregnancies (HOMP) are uncommon, the reported incidence range from 0.01% to 0.07% of all pregnancies. (1) (2) (3) Spontaneous quadruplet pregnancy is rare with an incidence rate of 1 in 512000 to 1 in 677, 000 births (2) The incidence of multiple pregnancies has increased dramatically in the last 25 years (4) (5) In United States it is documented that HOMP has increased fourfold during the 1980s and 1990s (6), due to infertility treatments like Assisted Reproductive Techniques (ART) and ovulation-inducing treatments (7) (8)…”

Section: Introductionmentioning

confidence: 99%

Fetal Reduction in High Order Pregnancy; A Retrospective Observational Study

Taha

Ibrahim

Amu

et al. 2021

Preprint

View full text Add to dashboard Cite

Background:High order multiple pregnancy (HOMP), is considered a high-risk pregnancy as it has many complications on the mother and the fetuses, with a huge financial burden on the hospitals. Therefore avoiding HOMP is important, however, if this fails, fetal reduction is an acceptable alternative procedure to reduce maternal complications and improve fetal outcome.Our aim to study the impact of a fetal reduction on the risk of preterm labour and postpartum hemorrhage in HOMP (More than Triplet).Methods:This is a retrospective study of all HOMPs seen during the period from July 2007 to July 2017 at Women’s Hospital- Hamad General Hospital, Doha, Qatar. We examined records of 50 women diagnosed with HOMP, incomplete records, and triplet pregnancies were excluded from the study. the data were collected from the ultrasound software as well as maternal files. Results:Of the 50 women diagnosed with HOMP, 39 quadruplets, 7 quintuplets.2 sextuplets and 2 septuplets. 56% had an ovulation induction, 26% had an IVF, 14% had an IUI, and 2 cases (4%) were spontaneous pregnancies.(28%) had a fetal reduction, with a mean gestation age of 12.64 ± 0.74 weeks of gestation, and with no immediate complications. Our study showed that there is no significant difference at time of delivery between reduced and non reduced group mean gestational age at the time of delivery for the reduced group was 30.26 ± 4.38, and 29.39 ± 4.78 weeks for the non-reduced group. P-value of 0.565 , 95% CI (-2.159-3.90). 44.9% had postpartum haemorrhage with a mean estimated blood loss of 1659.1 ± 958.5 mls. Our study showed that there is significant decrease in estimated blood loss in reduced group compared with non-reduced group with p-value of 0.047 ConclusionHigh order multiple pregnancies are a result of modern infertility treatments has significant serious adverse effects on the mother and the babies. Although fetal reduction reduced the rate of PPH but did not significantly improve the rate of preterm labour, hence prevention of HOMP is the primary goal.

show abstract

Spontaneous monochorionic tetra-amniotic quadruplet pregnancy at term

Cited by 8 publications

References 5 publications

Successful Management of Quadruplet Pregnancy following Spontaneous Conception

Successful Management of Quadruplet Pregnancy following Spontaneous Conception

Quadruplets and Quintuplets

Fetal Reduction in High Order Pregnancy; A Retrospective Observational Study

Contact Info

Product

Resources

About