Spontaneous Leiomyosarcoma Arising from the Ethmoid Turbinate of a Rat

Abstract

Spontaneous leiomyosarcoma arising from the left ethmoid turbinate was observed microscopically in an 83-week-old male F344 rat. The tumor cells showed smooth-muscle differentiation with prominent nuclear pleomorphism and a small number of mitotic figures. The tumor cells were also immunohistochemically positive for smooth-muscle actin. The tumor protruded slightly into the nasal cavity and invaded the surrounding tissues. The present article is the first case of spontaneous leiomyosarcoma in the rat nasal cavity.

Vaginal leiomyosarcoma in a degu (Octodon degus): a case report

“…They are much less common than leiomyomas but have been reported in some rodent species such as rat and hamster (Solleveld, 1987;Ribas and Pletcher, 1996;Kondo et al, 2007;Kasahara et al, 2009). The present report details a case of a spontaneous vaginal leiomyosarcoma occurring in a pet degu.…”