Spontaneous healing of aneurysmal bone cysts. A report of three cases

Maldague, Baudouin; Esselinckx, Walter; Noel, H; Nayer, Philippe De; Vincent, A.

doi:10.1302/0301-620x.71b4.2768314

Cited by 104 publications

(52 citation statements)

References 23 publications

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“…Spontaneous healing of ABC has already been documented radiologically [11]. However, the fibroblastic and myofibroblastic cell proliferation accompanied by an osteoclastic and osteoblastic reaction, resembles giant cell reparative lesions or reactive heterotopic ossification (myositis ossificans).…”

Section: Discussionmentioning

confidence: 95%

Solid variant of aneurysmal bone cyst: a case report with bilateral involvement of the distal femoral metaphyses

Karabela-Bouropoulou

Liapi-Avgeri

Paxinos

1994

Vichows Archiv A Pathol Anat

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An extremely rare case of bilateral, symmetrical involvement of distal femoral metaphyses by the solid variant of aneurysmal bone cyst (ABC) in a boy aged 13 years is described. Although there is no difference between the conventional ABC and the solid variant in terms of clinical and radiological presentation, the lesion is solid, composed of fibrohistiocytic cells with abundant giant cells and/or areas of florid, heterotopic ossification, while aneurysmal channels are sparse or absent. The lesion needs to be differentiated from giant cell tumour of bone, when the osteoclastic component predominates, while fibrous dysplasia, osteoblastoma and even osteosarcoma need to be excluded any time ossification is prominent. Careful evaluation of the clinical, radiological and pathological findings is necessary.

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Section: Discussionmentioning

confidence: 95%

Solid variant of aneurysmal bone cyst: a case report with bilateral involvement of the distal femoral metaphyses

Karabela-Bouropoulou

Liapi-Avgeri

Paxinos

1994

Vichows Archiv A Pathol Anat

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“…A treatment holiday of 3 months was given to all patients after histopathologic confirmation based on reports of spontaneous healing of the lesion after bone puncture or trauma [28,41]. During this 3-month period, patients in both groups were instructed specifically to note any increase in pain or sudden appearance of pain and were followed up every 3 weeks for clinical assessment for change in size of swelling; radiographs were obtained every 6 weeks to assess spontaneous healing or rapid progression of the lesion.…”

Section: Methodsmentioning

confidence: 99%

Is Sclerotherapy Better than Intralesional Excision for Treating Aneurysmal Bone Cysts?

Varshney

Rastogi

Khan

et al. 2010

Clinical Orthopaedics &Amp; Related Research

120

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Background Minimally invasive approaches such as sclerotherapy have been introduced to treat aneurysmal bone cysts. Sclerotherapy has been associated with reasonable healing rates during the past two decades. However, it is unclear whether sclerotherapy compares with the more traditional extended curettage and bone grafting. Questions/purposes We therefore compared the healing rates and functional scores in patients having percutaneous repetitive sclerotherapy using polidocanol (Group 1) with those with intralesional excision (extended curettage with a high-speed burr) and bone grafting (Group 2) for treatment of aneurysmal bone cyst. Patients and Methods We randomly divided 94 patients into two treatment groups. We assessed healing rates (primary outcome measure), pain relief, time to healing and recurrence, hospital stay, and the Enneking functional score. Forty-five patients from Group 1 and 46 from Group 2 were available for study. The minimum followup was 3.2 years (mean, 4.4 years; range, 3.2-6

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“…• The lesion increases moderately in volume during the first months after biopsy, then decreases in size within 4 or 5 months, as described in cases 1 and 4 and in some cases reported in the literature [10,11]. In such cases, supervision must be continued and surgery might be avoided.…”

Section: Discussionmentioning

confidence: 87%

Active aneurysmal bone cysts in children: Possible evolution after biopsy

Louahem

Kouyoumdjïan

Ghanem³

et al. 2012

Journal of Children's Orthopaedics

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Purpose The active or aggressive character in certain localisations of aneurysmal bone cysts in children requires either curettage with a considerable recurrence rate or a radical segmental excision, raising complex reconstructive challenges. Cyst maturation with subsequent ossification may be observed either spontaneously or after incisional biopsy. Patients Five new cases of active aneurysmal bone cysts (ABCs) with healing of the cyst after biopsy alone are reported. All patients had no treatment of the cyst after the biopsy. Results In two cases, the lesion initially increases in size immediately after the biopsy, and it is only secondarily that the lesion decreases in size. Four out of five cases of the spontaneous healing occurred in pelvic bone. The cysts healed after, respectively, 36, 24, 12, 32 and 12 months. Conclusions The emergence of these new cases of spontaneous healing encourages promoting clinical and radiological supervision after biopsy in selected cases. Unfortunately, it is impossible to predict a possible aggressive behaviour in ABCs. Then, if the lesion is quickly aggressive with clinically and radiologically increasing size after biopsy, it would be illogical and dangerous to let this ABC evolve. It would be necessary to treat it without delay. On the other hand, if the lesion moderately increased after the biopsy, it is possible to wait and observe the patient during a period of 5 months for a possible healing, if the ABC localisation is not dangerous. Of course, if the lesion does not increase in size after biopsy, there is no delay to treat it.

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Spontaneous healing of aneurysmal bone cysts. A report of three cases

Cited by 104 publications

References 23 publications

Solid variant of aneurysmal bone cyst: a case report with bilateral involvement of the distal femoral metaphyses

Solid variant of aneurysmal bone cyst: a case report with bilateral involvement of the distal femoral metaphyses

Is Sclerotherapy Better than Intralesional Excision for Treating Aneurysmal Bone Cysts?

Active aneurysmal bone cysts in children: Possible evolution after biopsy

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