Spontaneous Fracture of Right Tibia and Fibula in a Case of Locomotor Ataxia

Griffiths, Joseph

doi:10.1136/bmj.1.1895.1036

Cited by 3 publications

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“…Prevention: There are two clinical trials on the effectiveness of rehabilitation interventions in cerebellar ataxias. Ilg et al performed a prospective neurorehabilitation study on 15 individuals with hereditary cerebellar ataxias, three of whom had SCAs [ 71 ]. They discovered that four weeks of intense coordination training with three one-hour weekly sessions dramatically lowered known markers of falling risk such as the Berg Balance Scale (BBS) scores and improved motor performance and ataxia symptoms.…”

Section: Resultsmentioning

confidence: 99%

“…Although there are multiple lines of evidence that show high-intensity, customized physical rehabilitation programs, particularly for gait and balance training, can enhance motor function, the impact on lowering falls has seldom been studied. The studies Ilg et al [ 71 ] and by Santo de Oliveira et al [ 73 ] provide some information on the efficacy of rehabilitation therapies on the risk for unintentional falls, although they did not primarily monitor fall frequency but only indirect indicators for fall risk. There is a similar pattern in neuro-rehabilitation research for HD patients: Although HD patients consistently appeared to benefit from intensive rehabilitation in terms of improving function, mobility, ataxia, and balance, the number of falls was not reported as an outcome measure in most of the studies.…”

Section: Discussionmentioning

confidence: 99%

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Accidental Falls in Patients with Hyperkinetic Movement Disorders: A Systematic Review

Homann¹,

Homann²,

Ivanic³

et al. 2022

Tremor and Other Hyperkinetic Movements

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Background:The significance of falls and their repercussions in Parkinson's disease has been extensively researched. However, despite potentially serious effects on health and quality of life and negative impact on the healthcare system, there is not a sufficient understanding of the role of falls in hyperkinetic movement disorders (HKMDs). This review aims to provide an overview of the prevalence of falls, injuries, and preventive measures in the most common HKMDs.Methods: Studies up to May 1, 2022 were searched in PubMed using Medical Subjects Headings of relatively prevalent HKMDs associated with the terms "accidental falls", "injuries", "fractures", and "accident prevention".Results: In our review of 37 studies out of 155, we found evidence that for several HKMDs, such as spinocerebellar ataxia, essential tremor, Huntington's disease, and dystonia, fall risk is increased. Falls were reported in up to 84% of spinocerebellar ataxia patients, 59% of essential tremor patients, and 79% of Huntington's patients, with 65% of the latter falling frequently. Injuries occurred in up to 73% in Huntington and 74% in ataxia patients. Most of the common diseases characterized by HKMDs were investigated for both fall causes and consequences, but prevention studies were limited to spinocerebellar ataxia and Huntington's disease. Discussion:The limited available data suggest that patients with several HKMDs can be considered to be at increased risk of falling and that the consequences can be serious. As a result, physicians should be advised to include fall exploration in their routine workup and provide advice for safer mobility. In general, more research into fall-related concerns in HKMDs is necessary. Highlights:In contrast to Parkinson's disease, the prevalence of accidental falls, their repercussions, and preventive strategies are under-investigated in hyperkinetic movement disorders (HKMDs). Several HKMDs such as essential tremor, ataxia, and Huntington's disease have reported fall rates of up to 84% and fall-related injury rates of up to 74%. Therefore, routine examinations of HKMD patients should include a fall exploration and provide advice on safe mobility.

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Section: Resultsmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%