Spontaneous Decalcification of a Choroidal Osteoma

Trimble, Susan N.; Schatz, Howard; Schneider, G

doi:10.1016/s0161-6420(88)33144-1

Cited by 42 publications

(24 citation statements)

References 14 publications

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“…Growth may occur in over 40% of cases if followed for long enough. 169 Conversely, spontaneous decalcification 179,180 or involution 181 of a choroidal osteoma has also been observed.…”

Section: Primary Choroidal Tumoursmentioning

confidence: 99%

Things that go bump in the light. The differential diagnosis of posterior uveal melanomas

Rennie

2002

Eye

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“…Growth may occur in over 40% of cases if followed for long enough. 169 Conversely, spontaneous decalcification 179,180 or involution 181 of a choroidal osteoma has also been observed.…”

Section: Primary Choroidal Tumoursmentioning

confidence: 99%

Things that go bump in the light. The differential diagnosis of posterior uveal melanomas

Rennie

2002

Eye

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“…9,12,23,24 In particular, Trimble and colleagues 12,23 reported two cases of complete decalcification of choroidal osteoma, where both patients had received photocoagulation treatment for subretinal neovascularisation. It is not known whether the photocoagulation was the cause of the complete resolution or whether an increased level of laser-induced osteoclastic activity was the mechanism involved in the decalcification.…”

Section: Discussionmentioning

confidence: 99%

“…When choroidal neovascularisation occurs, laser photocoagulation may be useful. [7][8][9]23,[26][27][28] Some neovascular membranes associated with choroidal osteoma have not been amenable to treatment. 11,21 The apparent lack of success with laser treatment is due to the depigmentation of the RPE, which lessens the absorption of laser energy necessary to close the new vessels.…”

Section: Discussionmentioning

confidence: 99%

Choroidal osteoma: evidence of progression and decalcification over 20 years

Chen

Lee

Gass

2006

Clinical and Experimental Optometry

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Choroidal osteoma is a rare, benign, ossifying tumour of the choroid of unknown aetiology. In contrast to other types of intraocular ossification, choroidal osteoma is found typically in young healthy females in the second or third decades of life with no history of systemic or ocular disease. Choroidal osteoma is a deep, pale yellow lesion with distinct geographic borders at the juxtapapillary or macular region, with branching 'spider' vessels on the surface of the tumour. These features should help differentiate choroidal osteoma from other types of intraocular tumour and the diagnosis can be confirmed with ultrasonography and computerised tomography. Here we report an initially unilateral case of choroidal osteoma, which decalcified over 20 years but during the same period the fellow eye also developed a choroidal osteoma to become a bilateral case. Despite the benign nature of the tumour, vision may be compromised by gradual atrophy of the overlying retina, serous retinal detachment, accumulation of sub-retinal fluid and sub-retinal haemorrhage associated with choroidal neovascularisation. Frequent examinations are recommended for patients with choroidal osteoma, for early detection of a subretinal neovascular membrane and potential treatment with laser photocoagulation.

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“…Occasionally decalcification can occur and is characterized by thin, atrophic regions with associated retinal pigment epithelium (RPE) atrophy. 4,5 Decalcification can occur spontaneously or as a result of laser photocoagulation or photodynamic therapy. 6 Choroidal neovascular membrane (CNVM) may also develop.…”

Section: Introductionmentioning

confidence: 99%

Seven-year Follow-up of Clinical Course of Choroidal Osteoma: A Case Report

Nagpal¹,

Hassan²,

Mehrotra³

et al. 2012

WJORV

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An 18-year-old male was clinically diagnosed as having choroidal osteoma in August 2005. Ocular examination revealed 4 disk diameter orange colored elevated lesion in the left eye. Ultrasonography and computed tomographic (CT) scan of orbit, fluorescein angiogram (FA) and optical coherence tomography (OCT) confirmed the diagnosis of choroidal osteoma. The patient was followed up at regular intervals and on the 4th year followup developed a choroidal neovascular membrane (CNVM) within the osteoma. It was treated with intravitreal bevacizumab. Patient was stable for next 2 years followed by a recurrence of the membrane for which further injections were given to regress it. During this period there was consistent progression of the size of osteoma as well as its decalcified component. We documented progression of the osteoma along with regression of the CNVM with color photo and OCT for 7 years. Spectral domain features of the osteoma were noted in relation to changes occurring in its decalcified area.Long-term follow-up suggests that choroidal osteoma along with the decalcification part within it progresses with time. Intravitreal bevacizumab is effective in treating the CNVM secondary to choroidal osteoma.

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Spontaneous Decalcification of a Choroidal Osteoma

Cited by 42 publications

References 14 publications

Things that go bump in the light. The differential diagnosis of posterior uveal melanomas

Things that go bump in the light. The differential diagnosis of posterior uveal melanomas

Choroidal osteoma: evidence of progression and decalcification over 20 years

Seven-year Follow-up of Clinical Course of Choroidal Osteoma: A Case Report

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