Spontaneous Coronary Artery Embolus Associated With Calcific Aortic Stenosis

Stroke as the First Manifestation of Calcific Aortic Stenosis

“…Mansur et al [12]reported a case of CAS where myocardial infarction was the first manifestation of heart disease. Salka et al [13], in another case report, discuss what factors may contribute to the embolic phenomenon in stroke: a greater amount of calcium on the valve, aortic valve stenosis with concomitant regurgitation, and bicuspid aortic valves may all contribute to an embolic potential. We found only one instance where presumed SCE occurred to the cerebral and coronary circulations in the same patient [13], manifesting as transient ischemic attacks and myocardial infarction.…”

Stroke secondary to calcific bicuspid aortic valve: Case report and literature review

“…The embolization from calcific aortic valves varies from calcium deposits to non-calcific (thrombus) embolization. The amount of valvular calcium, the presence of mixed disease including, aortic valve stenosis with concomitant regurgitation, and bicuspid aortic valves (causing turbulence with release of adenosine diphosphate and partial thromboplastin from damaged erythrocytes) have been suggested as risk factors contributing to stroke [7,8].…”

Calcific retinal embolism as an indicator of severe unrecognised cardiovascular disease

“…2 5 Temporal arterioles were the sites of CRE in most of our patients, similar to the findings in other series. 1 9 Systemic calcium embolisation from calcified cardiac valves is not unusual and can have devastating clinical consequences, such as myocardial ischaemia or infarction [10][11][12] and cerebral infarction. [13][14][15] Holley and colleagues 16 reported that 31 of 165 patients (19%) with necropsy proven calcific aortic stenosis (85% moderate to severe) had pathological evidence of systemic calcium embolisation, but only one patient had CRE.…”