Spontaneous coronary artery dissection: Case report and review of literature

Biswas, Monodeep; Sethi, Arjinder; Voyce, Stephen J.

doi:10.4103/1995-705x.105737

Cited by 16 publications

(15 citation statements)

References 28 publications

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“…It has been commonly described among young women during the early postpartum period. The presumably hypertensive trauma during childbirth, increased shear stress on the arterial wall, decreased collagen production and haemorrhagic disruption of the vasa vasarum are the contributing factors to an intimal tear and cause blood entry into the media 1. Dissection is commonly observed at LAD (75%) and right coronary artery (20%).…”

Section: Discussionmentioning

confidence: 99%

Spontaneous coronary artery dissection: a rare cause of acute coronary syndrome

et al. 2014

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Spontaneous coronary artery dissection (SCAD) is a rare cause of acute myocardial infarction, which should always be included in differential diagnoses of acute coronary syndrome among young patients without known atherosclerotic risk. Although, it is commonly observed in young women during postpartum period, there were cases reported in connective tissue disorders, eosinophilic arteritis, contraception use, cocaine abuse and repetitive chest trauma. We report a case of SCAD, presenting with acute ST-elevation myocardial infarction, which was successfully treated conservatively.

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Section: Discussionmentioning

confidence: 99%

Spontaneous coronary artery dissection: a rare cause of acute coronary syndrome

et al. 2014

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“…Up to 30 % of cases of SCAD occur in the peripartum period. The mechanism appears related to the normal physiological state of pregnancy, in which increased cardiac output and blood volume place increased stress on the coronary arterial wall, already made more vulnerable due to hormonal effects on the intercellular matrix and the endothelium [32,103,104]. SCAD is not the only cause of AMI in pregnancy.…”

Section: Pathophysiology Of Coronary Heart Diseasementioning

confidence: 97%

Women and heart disease, the underrecognized burden: sex differences, biases, and unmet clinical and research challenges

Westerman

Wenger

2016

Clinical Science

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For many years the significance of heart disease in women was vastly underappreciated, and women were significantly underrepresented in cardiovascular clinical research. We now know that cardiovascular disease is the leading cause of death for women. Women and men share many similarities in the pathophysiology and manifestations of heart disease. However, as research advances with the continued inclusion of more women, knowledge about gender differences between the female and male heart, both on a physiological and pathophysiological basis, grows. These differences can be found in all domains of cardiovascular health and disease, including heart rhythm, heart failure, coronary disease and valvular disease. Further understanding of gender differences in the heart is crucial for advancing our ability to maintain a healthy population and identify and treat heart disease in both women and men. Specific examples within the spectrum of heart disease will be discussed in this review paper, and areas for further research will be proposed.

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“…There is no evidence that one approach is superior to another [20]. The medical, interventional, and surgical management approaches have all been reported to be effective [21,22].…”

Section: )mentioning

confidence: 99%

“…However, other vessels can also be involved: left main artery (4%-8%), right coronary artery (20%), and left circumflex coronary artery (4%) [11]. The diagnosis is usually confirmed by coronary angiography [12]. The common findings are the presence of an intimal flap, two separate communicating lumens, multiple dissecting lines, and an aneurysm communicating with the lumen.…”

Section: Case Reportmentioning

confidence: 99%

A Case of Post-partum Spontaneous Coronary Artery Dissection with Pulmonary Embolism: Survival with Thrombectomy and Stent Implant.

Thei¹

2015

J Clin Case Rep

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Spontaneous Coronary Artery Dissection (SCAD) is a rare life-threatening cause of acute coronary syndrome. It can affect young patients without atherosclerotic risk factors, particularly women in the antepartum or early post-partum period, as well as geriatric patients at high risk for atherosclerotic disease. The pathogenesis linking SCAD with pregnancy has not been fully elucidated. The few reported cases of SCAD in the setting of concomitant Pulmonary Embolism (PE) may highlight a potential mechanism in the pregnant or postpartum woman. Heretofore, cases of SCAD with the setting of pulmonary embolism have all been treated conservatively with medical therapy. We herein report a case of SCAD in the left anterior descending artery resulting in Non-ST elevation myocardial infarction and low ejection fraction associated with an acute pulmonary embolism in a young post-partum patient who was treated successfully with thrombectomy followed by stent placement. Her cardiac function returned to normal within six months with no recurrence of symptoms. To our knowledge, this is the first case of SCAD in the setting of pulmonary embolism who was successfully treated with thrombectomy and stent placement.

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Spontaneous coronary artery dissection: Case report and review of literature

Cited by 16 publications

References 28 publications

Spontaneous coronary artery dissection: a rare cause of acute coronary syndrome

Spontaneous coronary artery dissection: a rare cause of acute coronary syndrome

Women and heart disease, the underrecognized burden: sex differences, biases, and unmet clinical and research challenges

A Case of Post-partum Spontaneous Coronary Artery Dissection with Pulmonary Embolism: Survival with Thrombectomy and Stent Implant.

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