2016
DOI: 10.1002/ccr3.592
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Spontaneous bilateral patellar tendon rupture: case report and review of fluoroquinolone‐induced tendinopathy

Abstract: Key Clinical MessageThe present case emphasizes the importance of adhering to strict indications when prescribing fluoroquinolones. Although rare, drug‐induced tendinopathy is not confined to fluoroquinolones. The patient's and physician's awareness should be increased to reduce fluoroquinolones‐associated morbidity, particularly in patients with previously described risk factors.

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Cited by 17 publications
(10 citation statements)
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References 16 publications
(18 reference statements)
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“…These histologic changes result in the weakening of the tendon, thus predisposing rupture [ 2 , 10 - 11 ]. In addition to these three main categories, several case reports have described of fluoroquinolone-associated bilateral patellar tendon rupture [ 3 - 4 , 12 ].…”
Section: Discussionmentioning
confidence: 99%
“…These histologic changes result in the weakening of the tendon, thus predisposing rupture [ 2 , 10 - 11 ]. In addition to these three main categories, several case reports have described of fluoroquinolone-associated bilateral patellar tendon rupture [ 3 - 4 , 12 ].…”
Section: Discussionmentioning
confidence: 99%
“…Typically, bilateral tendon injury has been associated with systemic diseases such as renal failure, diabetes mellitus, rheumatoid arthritis, systemic lupus erythematosus, or a combination of those diseases [ 22 33 ]. Furthermore, several authors reported a correlation between tendon rupture and the use of steroids and fluoroquinolones [ 34 38 ]. All the aforementioned factors are accused of weakening collagenous structures and the structural integrity of the tendons, leading to their rupture.…”
Section: Discussionmentioning
confidence: 99%
“…Moreover, cases have been reported in apparently healthy people [8], and during sports activities [9]. Treatments like CS [10], FQ [11] and statins [12] also predispose to BPTR.…”
Section: Discussionmentioning
confidence: 99%