Spontaneous bacterial peritonitis with a very high leukocyte count in ascitic fluid caused by Haemophilus influenzae

Saadi, Tarek; Khoury, Safie; Veitsman, Ella; Baruch, Yaacov; Raz-Pasteur, Ayelet

doi:10.2147/ijgm.s49658

Cited by 4 publications

(4 citation statements)

References 7 publications

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“…24,25 Cases of spontaneous bacterial peritonitis due to Haemophilus influenza in an alcoholic cirrhosis patient have been reported recently. 26 Pasteurellaceae such as Haemophilus are common inhabitants of mucosal surfaces of the human upper gastrointestinal tract. 27 It is well known that small intestinal bacterial overgrowth is a risk factor that facilitates BT in cirrhosis.…”

Section: Discussionmentioning

confidence: 99%

“…Pasteurella can be involved in systemic infections such as bacteremia, meningitis, and peritonitis, often associated with cirrhosis and immune suppression . Cases of spontaneous bacterial peritonitis due to Haemophilus influenza in an alcoholic cirrhosis patient have been reported recently . Pasteurellaceae such as Haemophilus are common inhabitants of mucosal surfaces of the human upper gastrointestinal tract .…”

Section: Discussionmentioning

confidence: 99%

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Gut dysbiosis in acute‐on‐chronic liver failure and its predictive value for mortality

Chen

Guo

Qian

et al. 2015

J of Gastro and Hepatol

148

110

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Gut dysbiosis in acute‐on‐chronic liver failure and its predictive value for mortality

Chen

Guo

Qian

et al. 2015

J of Gastro and Hepatol

148

110

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“…Similarly, Saadietal, et. al., 22 explained that a higher neutrophil count in ascitic fluid is an accurate and earlier indicator of SBP when utilizing an index of >250/mm3 ascitic neutrophils.…”

Section: Discussionmentioning

confidence: 99%

Neutrophil Gelatinase-associated Lipocalin-2 and Macrophage antigen -1 in Cirrhotic Patients Infected with Carbapenem Resistant Enterobacteriaceae

Khalil

Mandour²,

Bedira³

et al. 2023

Egyptian Journal of Medical Microbiology

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Background: Early detection of bacterial infection in patients with cirrhosis remains a hope for improved prognosis to decrease the morbidity and mortality rate.Objective: To study the diagnostic importance of Neutrophil gelatinase-associated lipocalin-2 and macrophage antigen -1 for early detection of infection in cirrhotic patients and their relationship with carbapenem resistant bacteria. Methodology: 150 patients were divided into group I: cirrhotic patients complicated with infection subdivided into three subgroups; A: fifty-five patients with spontaneous bacterial peritonitis (SBP), Subgroup B: fifteen patients with culture-negative neutrocytic ascites (CNNA) and subgroup C: thirty patients with urinary tract infection. Group II: fifty cirrhotic patients without infections. NGAL-2 estimation was done by ELISA, neutrophil MAC-1 by flowcytometry and Carbapenem resistance genes; OXA-48 and KPC-3 were detected by RFLP-PCR analysis Results: Significant increase of ascitic fluid neutrophils and WBCs count in SBP subgroup. Mean fluorescence intensity of Mac-1 and NGAL-2 concentrations were significantly higher in cirrhotic infected than uninfected patients. The OXA-48 and KPC-3 Carbapenem resistant gram-negative bacteria were prevalent among cirrhotic infected patients. NGAL-2 can detect early infection in cirrhotic patients followed by Mac-1. Conclusion: NGAL-2 and Mac-1 could be used for early detection of bacterial infection in cirrhotic patients with high specificity and sensitivity.

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“…Infeksi ini pada umumnya disebabkan oleh beberapa mikroorganisme diantaranya: Escherichia coli, Klebsiella pneumoniae, dan organisme gram negatif lainnya (Saadi et al, 2013). Lebih dari 95% kasus peritonitis bakterial idiopatik (SBP) terjadi akibat transmisi bakteri (Bruns T et al, 2015).…”

Section: ) Infeksiunclassified

Cegah dan Kenali Kondisi Hati (CEK SI HATI) sebagai Upaya Pendidikan Kesehatan terkait Sirosis Hati Kepada Masyarakat

Nurrofikoh,

Fatima,

Hastuti

et al. 2023

Creat J. Cumn Enga

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ABSTRAK Sirosis hati dikaitkan dengan kebiasaan minum alkohol, racun, kondisi keturunan, atau proses autoimun dan infeksi bakteri terkait organ hati. Penyakit ini ditandai pengerasan hati yang disebabkan oleh adanya jaringan parut atau fibrosis. Pencegahan penyakit hati selain alkoholisme adalah kebersihan makanan dan minuman yang dikonsumsi serta hygiene tangan. Untuk itu, upaya pencegahan melalui Pendidikan Kesehatan sangat penting. Program Pengabdian Kepada Masyarakat (PKM) ini bertujuan untuk mengidentifikasi tingkat pengetahuan terkait penyakit hati sebelum dan sesudah pendidikan kesehatan terkait dengan sirosis hati untuk masyarakat. Metode edukasi yang dilakukan adalah ceramah, tanya jawab dan menonton video. 52 partisipan mengikuti edukasi dan mengisi pertanyaan pre-test dan post-test sebagai bahan evaluasi. Dalam menilai hasil pre-test dan post-test digunakan 10 pertanyaan multiple choise, selanjutnya pengetahuan peserta dikelompokkan kurang jika nilai mencapai diantara angka 10-40, cukup jika mencapai rentang 50-70, dan sangat baik jika berada dalam rentang 80-100. Hasil menunjukkan nilai rata-rata pengetahuan partisipan meningkat dari 61.92 pada pre test menjadi pada post test 84.04. Hal ini menunjukkan bahwa ceramah, tanya jawab dan menonton video edukasi terkait sirosis hati dapat meningkatkan wawasan masyarakat, sehingga dapat melakukan upaya pencegahan terhadap penyakit ini. Diharapkan pada masa yang akan datang dapat dilakukan edukasi serupa secara serial termasuk mengukur pola hidup beresiko pada partisipan. Kata Kunci: Alkohol, Edukasi, Sirosis Hati, Pencegahan ABSTRACT Cirrhosis of the liver is associated with drinking alcohol, toxins, hereditary conditions, or autoimmune processes, and bacterial infections associated with the liver. This disease is characterized by fibrosing of the liver and caused by the presence of scar tissue or fibrosis. Prevention of liver disease besides alcoholism is the cleanliness of the food and drink consumed and hand hygiene. For this reason, prevention efforts through Health Education are very important. This Community Service Program (PKM) aims to identify the level of knowledge related to liver disease before and after health education related to cirrhosis of the liver in the community. The educational methods used are lectures, question and answer, and watching videos. 52 participants took part in the education and filled out pre-test and post-test questions as evaluation material. In assessing the results of the pre-test and post-test, 10 multiple-choice questions were used. Furthermore, participants' knowledge was grouped as lacking if the score reached between 10-40, sufficient if it reached the 50-70 range, and very good if it was in the 80-100 range. Results showed that the average value of the participant’s knowledge increased from 61.92 in the pre-test to 84.04 in the post-test. This shows that lectures, questions and answers and watching educational videos related to cirrhosis of the liver can increase public awareness so that they can make efforts to prevent this disease. It is hoped that in the future similar education can be carried out serially including measuring risky lifestyles in participants. Keywords: alcohol, cirrhosis, education, liver, prevention

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Spontaneous bacterial peritonitis with a very high leukocyte count in ascitic fluid caused by Haemophilus influenzae

Cited by 4 publications

References 7 publications

Gut dysbiosis in acute‐on‐chronic liver failure and its predictive value for mortality

Gut dysbiosis in acute‐on‐chronic liver failure and its predictive value for mortality

Neutrophil Gelatinase-associated Lipocalin-2 and Macrophage antigen -1 in Cirrhotic Patients Infected with Carbapenem Resistant Enterobacteriaceae

Cegah dan Kenali Kondisi Hati (CEK SI HATI) sebagai Upaya Pendidikan Kesehatan terkait Sirosis Hati Kepada Masyarakat

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